An individual's sense of themselves as a "STEM person" is largely formed through recognition feedback. Unfortunately, for many minoritized individuals who engage in STEM (science, technology, engineering, and mathematics) in formal and informal spaces, this recognition often adheres to long-standing exclusionary expectations of what STEM participation entails and institutionalized stereotypes of what it means to be a STEM person. However, caregivers, who necessarily share cultural backgrounds, norms, and values with their children, can play an important role in recognizing their children's interest and inclination towards STEM in ways that support children's authoring of their STEM identity in the face of these marginalizing discourses. To explore this idea, we conducted phenomenological interviews with STEM students attending a Hispanic-serving university, examining the nature of STEM-related conversations these students had with their parents during childhood. Participant recollections provide evidence of conversational content, contexts, and structures that supported their identification with STEM even when faced with marginalizing experiences. We found that though this phenomenon was recounted across parent profiles, participant narratives also reflected differences in conversation content, context, and structure based on factors associated with STEM
La Esclerosis Múltiple (EM) es una enfermedad crónica del sistema nervioso central, para la cual aún no hay una cura definitiva; sin embargo, existe una diversa variedad de terapias con el objetivo de modificar el curso natural de la enfermedad, que promueve la inclusión constante de nuevas estrategias terapéuticas. Objetivo: La Sociedad Peruana de Neurología, por encargo del Ministerio de Salud, convocó a un comité de expertos con el objetivo de elaborar una guía de práctica clínica para el diagnóstico y tratamiento de EM. Método: Se realizó una búsqueda y evaluación de guías de práctica clínica bajo la metodología AGREE II, escogiendo como modelo la Guía de Práctica Clínica Catalana. Las preguntas clínicas no concernientes al tratamiento fueron resueltas a través de revisión sistemática. Las preguntas clínicas de tratamiento se diseñaron bajo el formato PICO y se resolvieron con un meta-análisis de ensayos clínicos disponibles hasta agosto del 2017, tomando en consideración las terapias aprobadas por DIGEMID hasta enero del 2017. Las recomendaciones finales fueron elaboradas mediante el método Delphi modificado con un consenso de al menos 80% de los miembros de su comité. Finalmente se realizó una revisión externa del manuscrito por expertos internacionales en EM. Resultados: Se formularon 18 preguntas clínicas y 21 recomendaciones para el manejo, incluyendo algoritmos terapéuticos.
BACKGROUND: Neuropsychiatric symptoms (NPS) in patients with Alzheimer’s disease (AD) worsened during the COVID-19 lockdowns, but their progression thereafter is unknown. We present the first longitudinal study tracking them before, during, and after restrictions. OBJECTIVES: To describe the effect of the COVID-19 mandatory lockdowns on Cognitive and Neuropsychiatric symptoms in patients with Mild Cognitive Impairment (MCI) and Alzheimer’s Disease (AD) METHODS: Cohort of 48 patients with amnestic MCI and 38 with AD in Lima, Peru. They received three rounds of cognitive (RUDAS, CDR, M@T), behavioral (NPI), and functional (ADCS-ADL) assessments. We assessed the change in score means across the time points and for each domain of NPS and tracked the changes in individual patients. RESULTS: RUDAS declined 0.9 (SD 1.0) from baseline to lockdown and 0.7 (SD 1.0) after restrictions. M@T declined 1.0 (SD 1.5) from baseline to lockdown and 1.4 (SD 2.0) after restrictions. CDR worsened in 72 patients (83.72%) from baseline to post-lockdown. NPI worsened by 10 (SD 8.3) from baseline to lockdown but improved by 4.8 (SD 6.4) after restrictions. Proportionally, 81.3% of all patients had worsened NPS during the lockdowns, but only 10.7% saw an increase thereafter. Improvement was statistically significant for specific NPS domains except hallucinations, delusions, and appetite changes. Anxiety, irritability, apathy, and disinhibition returned to baseline levels. CONCLUSION: Following confinement, cognition continued to decline, but NPS demonstrated either stability or improvement. This highlights the role modifiable risk factors may have on the progression of NPS
Artisanal fishing of aratu occurs throughout the northeastern coast, but their total catch is only estimated for three states, Pernambuco, Sergipe and Bahia. The aratu fishing is intense and few studies on the biology of the species, population dynamics and socioeconomic has been published. Therefore, this work aimed to characterize the population structure and reproductive aspects of G. cruentata, landed in the communities of Cajazeiras and Pontal, in Sergipe. The collections were made monthly when the new moon, from March 2015 to February 2016. The results showed that the carapace width (LC) of the animals ranged in Cajazeiras 25 to 53.8 mm and 59.6 mm in Pontal. Cajazeiras and Pontal showed different patterns for the percentage of females and males, considering the frequency of carapace width. Females were predominant in 26-48 mm class in Cajazeiras and in Pontal from 28 to 44 mm. The males were the majority in the longest lengths in Cajazeiras and Pontal, the result indicates that the males dominate in the longest lengths. Mature female maturation was found throughout the study with greater frequency in September in both mangroves studied. The estimated result of the wide average carapace at first maturity of females in Cajazeiras indicated value of 33.2 mm and males equal to 36.5 mm; Pontal for the female values was 31.2 mm and 36.8 mm male.
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