Coronavirus Disease 2019 (COVID-19) is believed to have emerged in Wuhan, China in late December 2019 and began rapidly spreading around the globe throughout the spring months of 2020. As COVID-19 proliferated across the United States, Asian Americans reported a surge in racially motivated hate crimes involving physical violence and harassment. Throughout history, pandemic-related health crises have been associated with the stigmatization and "othering" of people of Asian descent. Asian Americans have experienced verbal and physical violence motivated by individuallevel racism and xenophobia from the time they arrived in America in the late 1700s up until the present day. At the institutional level, the state has often implicitly reinforced, encouraged, and perpetuated this violence through bigoted rhetoric and exclusionary policies. COVID-19 has enabled the spread of racism and created national insecurity, fear of foreigners, and general xenophobia, which may be related to the increase in anti-Asian hate crimes during the pandemic. We examine how these crimessituated in historically entrenched and intersecting individual-level and institutional-level racism and xenophobiahave operated to "other" Asian Americans and reproduce inequality.
This article explores the diminished occurrence of intimate partner homicide (IPH)—referred to as self-help homicide—perpetrated by Latinas when compared with Black and White women. Self-help homicide is a consequence of patriarchal terrorism. I endeavor to answer the following research question: What explains lower rates of self-help homicide perpetrated by Latinas relative to White and Black women? This question is addressed through a self-help/intersectional theoretical analysis of structural, institutional, and cultural barriers to criminal justice resource access. This diminished access increases the likelihood of IPH victimization.
Affirmative action (AA) addresses individuals' exclusion from opportunities based on group membership by taking into account race, sex, ethnicity, and other characteristics. This chapter reviews sociological, economic, historical, and legal scholarship on AA. We first consider the emergence of group-based remedies, how protected groups are defined, and proportional representation as a standard for inclusion. We then summarize the research on AA in education (including busing) and in employment. The concluding section reviews societal responses to AA, including attitudes, challenges, and political responses. As public and judicial support for AA has waned, employers and educators have increasingly turned toward diversity as a rationale for including underrepresented groups. Despite this change, many employers and educators continue to take positive steps to include minorities and women.
This manuscript details the process research and development of a convergent and safe approach to 1 on a multikilo scale. Specific highlights of the process development efforts will be described, including the development of a dehydrogenation method for dihydropyrimidines and a thermochemically safe synthesis of a 1,2,4-aminotriazole fragment. A key feature of the synthesis is the use and optimization of a modified Julia-Kocienski olefination reaction. Specifically, we report an unprecedented dependence of the product olefin geometry on reaction temperature, where an E:Z ratio as high as 200:1 can be obtained. Initial insights into the mechanistic rationale for this observation are also provided. Finally, a purity upgrade sequence via an intermediate crystalline form is highlighted as a method of controlling the final API quality.
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