Aim: To assess the efficacy of the greyscale and Doppler ultrasound in the diagnosis of hepatoma in chronic liver disease patients. Study Design: Prospective study. Place and duration of study: Department of Radiology, Jinnah Postgraduate Medical Centre Karachi from 1st October 2021 to 30th June 2022. Methodology: One hundred and twenty patients who were diagnosed with chronic liver diseases and were suspected of hepatocellular carcinoma were included in this study. Ultrasonography was conducted under grey scale Doppler scanning in each patient after 6 hours of fasting at 3-6 megahertz with a curvilinear probe in supine as well as oblique position. Sensitivity, specificity as well as the predictive value of the image formed through the ultrasonography machine was assessed. Results: The age of the patients was 46.5±6.5 years and there were 78 (65%) males whereas 42 (35%) were females. On the grey scale Doppler scan, there was 53% of cases seen confirmed for the presence of hepatoma. The sensitivity and specificity were observed in 65% and 85% of the grey scale Doppler ultrasonography while the positive predictive value was 92% respectively. Conclusion: Greyscale Doppler scan is an efficient and reliable method for the detection of hepatoma and can be used in clinically confirmed cases of chronic liver disease as a screening tool. Keywords: Hepatoma, Greyscale, Doppler ultrasound, Chronic liver disease
Aim: To evaluate the role of high-resolution Computer tomography imaging in the management of COVID-19. Study design: Prospective study Place and duration of study: Jinnah Postgraduate Medical Centre Karachi from 1st December 2021 to 31st May 2022. Methodology: One hundred patients suspected to be suffering from COVID-19 were enrolled. All patients underwent Reverse transcriptase-based polymerase chain reaction tests (RT-PCR). The patients were divided into positive or negative depending upon their test results. A high-resolution computed tomography scan was followed in every patient and the results were compared with the reverse transcriptase-based polymerase chain reaction tests findings. The sensitivity and Specificity of the CT scan test were assessed. Results: The mean age of the patients was 59±6.5 years. There were 60 (60%) male and 40 (40%) female patients. Around 58% of the patients were found as positive on PCR while 42% were negative. There 75% of the cases were positive for novel coronavirus on high-resolution computed tomography scan while only 25% were negative. Conclusion: Chest HRCT-scan proved to be a better and more sensitive tool for the diagnosis of novel coronavirus and can be considered as an alternative screening tool for COVID-19 confirmation. Keywords: SARS-CoV-2, Severity, Pulmonary, CT-scan, Serotype
Aim: To evaluate black tea consumption as a negative contrast agent for better imaging of MRCP. Study design: Prospective study. Place and duration of study: Department of Radiology, JPMC Karachi from 1st January 2022 to 30th June 2022. Methodology: One hundred healthy individuals, who volunteered for this research, were provided an informed written consent to sign before their study enrolment. Tea bags from 3 different tea bag companies were used. The efficacy of improvement of MRCP image as a consequence of tea consumption was further noted by a standard procedure. The intensity of signals was measured by circular-ROI (1cm2). The intensity signal was based on noise and measured as signal void. The MRCP results were taken before tea intake after 5 minutes of tea intake and up to 15 minutes were performed. The results were observed through MRCP images. Results: Comparison of visibility in the distal part of the common bile duct by VAS and Likert method showed significant differences before and after the tea consumption and showed better image quality after tea consumption. Comparisons of duodenum and stomach according to VAS and Likert methods were statistically significant. Conclusion: Significant results were obtained after the consumption of black tea for better quality MRCP imaging. Keywords: MRCP; Tea consumption, Better quality imaging; Gastrointestinal system
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