The morphologic and functional damages of diabetes mellitus (DM) on microcirculation can play a role in the pathogenesis of both polyneuropathy and cerebral white matter lesions. The aim of this study is to investigate the relation between polyneuropathy and cerebral deep white matter lesions (DWMLs) and carotid atherosclerosis in patients with type 2 DM. Sixty-six patients with type 2 DM without any disorder that may cause polyneuropathy, and vascular risk factors except for DM and hyperlipidemia were included in the study. DWMLs and carotid atherosclerosis were investigated in patients with and without polyneuropathy. Forty patients (60.6%) had diabetic sensorimotor polyneuropathy. DWMLs were more frequent in patients with polyneuropathy compared to patients without polyneuropathy (p = 0.003). Logistic regression analysis confirmed association between polyneuropathy and DWMLs after adjusted for age (p = 0.013), duration of DM (p = 0.007), and both age and duration of DM (p = 0.016). No statistically significant difference was found between patients with and without polyneuropathy for carotid atherosclerosis. Among patients with polyneuropathy, those having DWMLs had higher mean age (p = 0.003) and longer symptom duration (p = 0.020) compared to patients without DWMLs. No association was found between DWMLs and carotid atherosclerosis. Polyneuropathy and cerebral DWMLs in type 2 DM patients may share common pathogenesis; presence and duration of polyneuropathy symptoms may predict ischemic white matter damage independent of carotid atherosclerosis.
No evidence of past WNV infection was found in our study population of MG patients. This may have been because MG has been showed to be related with neuroinvasive WNV, which none of our study subjects seem to have had based on their stories. New multicentre studies focusing on immunological mechanisms and held with larger groups or especially neuroinvasive disease patients can cast light onto the answer of this question.
ÖZRadial sinirin dirsek düzeyindeki etkilenimi; radial tünel sendromu ve posterior interosseöz sinir sendromu olarak iki farklı klinik tabloya neden olur. Radial tünel sendromu motor güçsüzlük oluşturmadan ağrı ve nadiren duyu bozukluğuna yol açarken; posterior interosseöz sinir sendromu elin ekstansör kaslarında güçsüzlük ile bulgu verir ve duyusal bozukluk izlenmez. Bu yazıda önkola travma sonrası sağ el üçüncü parmakta ekstansiyon kaybı gelişen ve elektronöromyografide posterior interosseöz sinir tuzaklanması saptanan bir hasta sunulmuş ve oldukça nadir karşılaşılan parsiyel posterior interosseöz sinir sendromunun, radial sinir tuzaklanmalarının ayırıcı tanısında akılda tutulmasının önemi vurgulanmıştır.
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