These findings suggest that MCs may upregulate tumor angiogenesis in oral SCC, perhaps via MC tryptase.

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There was no significant difference between intraoral film, a high-resolution complementary metal oxide semiconductor digital imaging system and CBCT in detecting vertical root fractures in mandibular single-rooted teeth.

Cone-beam computed tomography (CBCT) has been developed as a new imaging modality for dentists to diagnose various diseases and to determine treatment plan options. It can display the images in axial, sagittal, and coronal planes, as well as permitting three-dimensional (3D) image reconstruction. Therefore, CBCT is widely used in several dental applications.1 Recently, there have been studies on the accuracy in detection of caries using CBCT. 2-9 However, the effectiveness of CBCT in caries detection has been still equivocal. Akdeniz et al 2 found that limited cone beam computed tomography (LCBCT) was better to assess the depth of proximal caries than intra-oral digital imaging systems using storage phosphor plate sensors and film. The 3DX Accuitomo system (Mortita, Kyoto, Japan), one of the CBCT systems, was reported to show significantly higher sensitivity than 2D images in detecting proximal dentin caries. 4,5 For proximal enamel caries, Young et al 5 found that the 3DX Accuitomo was a superior imaging modality to intra-oral digital imaging systems using charge coupled device (CCD) sensors. Kayipmaz et al 7 stated that CBCT images could detect occlusal caries better than conventional films and storage phosphor plates, whereas no signifcant difference was found for proximal caries. Kamburoglu et al 9 found that CBCT images improved the detection of occlusal caries in deep enamel, superficial dentin, and ABSTRACTPurpose : The aim of this study was to compare the diagnostic accuracy of cone-beam computed tomography (CBCT) images and bitewing images in detection of secondary caries. Materials and Methods : One hundred and twenty proximal slots of Class II cavities were randomly prepared on human premolar and molar teeth, and restored with amalgam (n= =60) and composite resin (n= =60). Then, artificial secondary caries lesions were randomly created using round steel No. 4 bur. The teeth were radiographed with a conventional bitewing technique and two CBCT systems; Pax-500ECT and Promax 3D. All images were evaluated by five observers. The area under the receiver operating characteristic (ROC) curve (A z ) was used to evaluate the diagnostic accuracy. Significant difference was tested using the Friedman test (p value⁄0.05).Results : The mean A z values for bitewing, Pax-500ECT, and Promax 3D imaging systems were 0.882, 0.995, and 0.978, respectively. Significant differences were found between the two CBCT systems and film (p= =0.007). For CBCT systems, the axial plane showed the greatest A z value. Conclusion : Based on the design of this study, CBCT images were better than bitewing radiographs in detection of secondary caries. (Imaging Sci Dent 2011; 41 : 143-50)

The present study showed that the prevalence of PEIR in Thai samples is 1.63%. This could raise dentists' awareness in reviewing unerupted teeth in panoramic radiographs. Early detection of the lesions should aid in proper treatment planning of affected teeth to prevent complications from carious invasion after tooth eruption.