The placenta is a flattened discoidal mass . Placenta with various abnormal shape like bidiscoidal, low-patiented, placenta membranacae or diffuse, placenta succenturiata, circumvallate circummarginate placentae have been less encountered but very remotely studied in relevance to clinical significance. Placenta succenturiata is a bilobbed placenta , where there is one large and one small part, connected with membranous vessels. It is associated with antepartum haemorrhage, Vasa previa, postpartum haemorrhage, retained lobe of placentae and infection. Antepartum haemorhage due to placenta succenturiata appears to be uncommonly recorded in the literature. We describe a case of placenta succenturiata , presented with antepartum haemorrhage. By LSCS a living healthy male baby of 3.3 kgs was delivered. Ultimately the Internal Iliac arteries were ligated to stop lower uterine segment bleeding.Bangladesh J Obstet Gynaecol, 2015; Vol. 30(2) : 116-118
Abstract:Annular elastolytic giant cell granuloma (AEGCG) is a rare granulomatous dermatosis characterized by loss of elastic fibers and elastophagocytosis by multinucleated giant cells. It is characterized by annular plaques that are similar to those observed in granuloma annulare but that specifically appear in sun-exposed skin and occurs more commonly in females than males. There have been reported cases of AEGCG associated with diabetes mellitus, systemic sarcoidosis, cutaneous amyloidosis, molluscum contagiosum, squamous cell carcinoma of the lung and cutaneous T-cell lymphoma. We report a case of AEGCG in both sun-exposed as well as covered areas of a middle aged lady with hepatic nodules and Barret's esophagus.
Background: Psoriasis vulgaris is common papulosquamous disorder. Methotrexate (MTX) and cyclosporine, both of these drugs are in regular use for psoriasis management. But which one is superior in efficacy are yet to establish.
Aims and Objectives: The aim of the study was to compare efficacy of MTX and intermittent cyclosporine therapy in the management of extensive/severe psoriasis, and to find and compare the incidence of adverse effects/safety of both the drugs.
Materials and Methods: A randomized and controlled study was designed to compare the efficacy and safety of treatment. Patients with extensive psoriasis were randomly put in two groups –MTX and cyclosporine group and treated for 12 weeks.
Results: Psoriasis area severity index (PASI) gradually reduced in both group, that is, up to second visit of study, (4 Weeks after induction of study) the reduction was at par. After that, it reduced in Cyclosporine group significantly faster than MTX group. At the end of the study, that is, after 12 weeks, the difference of PASI in both groups was not significant.
Side-effects were not serious and minimal.
Conclusion: Both the drugs are effective, but Cyclosporine is faster in onset than MTX. Adverse effects are nominal and not serious.
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