Device migration and endoleaks were very infrequent after treatment with the Zenith AAA Endovascular Graft. However, endograft oversizing of >30% was associated with an approximately 14-fold increase in device migration (>5 mm) at 12 months and with a approximately 16-fold increased risk of AAA expansion at 24 months. Although further follow-up will be essential to assess whether these early associations continue, avoidance of excessive endograft oversizing is recommended.
Aortic endograft infection can be eradicated by excision and in situ or extra-anatomic replacement but is often associated with early postoperative morbidity and mortality and occasionally with a need for late removal for reinfection. Prosthetic graft replacement after explanation is associated with higher reinfection and graft-related complications and decreased survival compared with autogenous reconstruction.
Cilostazol significantly increased ACD at all measured time points and initial claudication distances at most time points. This agent may represent a new treatment option for patients with intermittent claudication.
Aortic neck angulation appears to be an important determinant of outcome after EAAA repair. Although patients with mild angulation (<40 degrees) had favorable outcomes in this series, those with moderate (40 to 59 degrees) or severe angulation (>or=60 degrees) had a 54% to 70% risk of one or more adverse events. Importantly, these outcomes occurred in spite of an adequate length (>2 cm) of proximal aortic neck. On the basis of these data, great caution should be exercised in recommending EAAA repair for patients with aortic neck angulation >or=40 degrees.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.