Primary cutaneous CD30 + lymphoproliferative disorders (LPDs) are a spectrum of diseases of which lymphomatoid papulosis (LyP) is the most common. 1 Rarely, LyP can occur in children. 2 LyP is characterized by recurrent crops of papules and nodules that spontaneously resolve. 3 Half of patients experience symptoms of pain and/or pruritus. 4 The prognosis of LyP is excellent with a 10year overall survival of 92%. 5 LyP is associated with a 14%-51.7% risk of developing a second lymphoma, most commonly mycosis fungoides. 6-8 Despite its benign nature, individuals with LyP can develop disfiguring scarring and pigmentary changes which may significantly affect their quality of life. We present a case of resistant LyP with significant scarring in a pediatric patient successfully treated with photodynamic therapy (PDT) and narrowband ultraviolet B (nbUVB).
Objective
To determine whether septal perforations have an effect on nasal swell body (NSB) size.
Study Design
Retrospective cohort study.
Setting
Two tertiary academic medical centers.
Methods
Computed tomography maxillofacial scans of 126 patients with septal perforation and 140 control patients from November 2010 to December 2020 were evaluated. Perforation etiology was determined. Measurements included perforation length and height and swell body width, height, and length. Swell body volume was calculated.
Results
The width and volume of the NSB are significantly smaller in perforation patients when compared to controls. The swell body is significantly smaller and thinner in perforations exceeding 14 mm in height compared to small perforations. Perforation etiology groupings into prior septal surgery, septal trauma, septal inflammatory, and mucosal vasoconstriction categories all demonstrated decreased swell body volume and width compared to controls. Inflammatory etiology had the greatest decrease in swell body size. The hemi‐swell body on the contralateral side of a septal deviation is significantly thicker than the ipsilateral side.
Conclusion
The NSB is smaller in patients with septal perforation regardless of perforation size or etiology.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.