Caucalis platycarpos L. and Eryngium caucasicum belong to Umbelliferae and are well represented in the flora of Iran by about 120 genera, 3500 species, and 100 endemic plants. This family is really valuable from economic and medicinal points of view and some species of this family are well known either because they have medicinal properties or because of great essential oils that they contain. Additionally, the mentioned genus has been wildly used in traditional medicine in Iran as an antitumor, antioxidant, antibacterial, and anti-inflammatory agent. In this regard, this study was conducted to provide useful information about essential oils of these two species. Volatile constituents of aerial parts of Caucalis platycarpos L. and Eryngium caucasicum Trautv. were investigated using gas chromatography/mass spectrometry (GC-MS) and gas chromatography/flame ionization detection (GC-FID). Antimicrobial activities of the essential oils were tested against Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa, and Bacillus subtilis using a disc diffusion method. The essential oils were mainly composed of trans-pinocarvyl acetate and caryophyllene oxide considered as the most significant constituents. According to a minimum inhibitory concentration (MIC) and a minimum bactericidal concentration (MBC), the essential oils showed antimicrobial effects. Moreover, the oils extracted from E. caucasicum and C. platycarpos indicated antibacterial activities against S. aureus and B. subtilis.
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