Aim: HCV treatment in people who actively inject drugs (PWID) (active PWID) is sometimes withheld. We propose that active PWID can be treated for HCV in the right setting. Methods: HCV-infected active PWID were evaluated at a multidisciplinary clinic in an observational study. The primary end point was a sustained virologic response following HCV therapy. Results: We included 40 active PWID, of which 63% used heroin, 70% used cocaine and 37% received all-oral regimens. With a mean follow-up of 570 days, 78% subjects achieved sustained virologic response (93% on all-oral regimens; p < 0.05), with no recurrent viremia. Conclusion: Active PWID can be effectively treated for HCV, especially with all-oral regimens and rates of recurrent viremia can be reduced in a multidisciplinary healthcare setting.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.