Papillary carcinoma is a rare malignant tumour of the breast with an incidence of 1-2% in the general population. The clinical behaviour of solid papillary carcinomas is generally indolent unless it is associated with invasion. Here, we are reporting two cases of solid invasive papillary carcinomas of the breast, who were 2 female patients aged 44 years and 55 years., with breast masses which were diagnosed by FNAC and confirmed by histopathology. The exact incidence and the clinical behaviours of such cases need to be ascertained by further research.
Neonatal sepsis is the third leading cause of neonatal mortality and an estimated 3 million newborns suffer from sepsis globally every year. Early diagnosis and treatment will go a long way in reducing the load. However, there is a lack of consensus on the definition and the accepted criteria for diagnosis of neonatal clinical sepsis in practice and research. The objective of this study was to assess the risk factors and laboratory parameters used in diagnosis of neonatal sepsis. A retrospective case control study was conducted among neonates admitted in the NICU. Blood parameters including total leukocyte count, immature/total neutrophil ratio, and C-reactive protein along with blood culture results were analyzed along with neonatal demographics and obstetric history. Although I/T ratio and CRP showed significant correlation with neonatal sepsis, positive blood culture results were found in 8.3% of the cases only. Hence the evaluation for presence of non-bacterial pathogens is an important consideration for a definition of neonatal sepsis and in particular, clinical sepsis.
Trichilemmal tumours are the tumours derived from the hair follicles. Malignant counterpart of these tumours is rarely encountered when compared to the benign ones. We present a case of recurrent malignant proliferating trichilemmal tumour in an elderly male
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