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Stroke is one of the prominent causes of death in the recent days. The existence of susceptible plaque in the carotid artery can be used in ascertaining the possibilities of cardiovascular diseases and long-term disabilities. The imaging modality used for early screening of the disease is B-mode ultrasound image of the person in the artery area. The objective of this article is to give a widespread review of the imaging modes and methods used for studying the carotid artery for identifying stroke, atherosclerosis and related cardiovascular diseases. We encompass the review in methods used for artery wall tracking, intima–media, and lumen segmentation which will help in finding the extent of the disease. Due to the characteristics of the imaging modality used, the images have speckle noise which worsens the image quality. Adaptive homomorphic filtering with wavelet and contourlet transforms, Levy Shrink, gamma distribution were used for image denoising. Learning-based neural network approaches for denoising give better edge preservation. Domain knowledge-based segmentation approaches have proved to provide more accurate intima–media thickness measurements. There is a requirement of useful fully automatic segmentation approaches, 3D, 4D systems, and plaque motion analysis. Taking into consideration the image priors like geometry, imaging physics, intensity and temporal data, image analysis has to be performed. Encouragingly more research has focused on content-specific segmentation and classification techniques. With the evaluation of machine learning algorithms, classifying the image as with or without a fat deposit has gained better accuracy and sensitivity. Machine learning–based approaches like self-organizing map, k-nearest neighborhood and support vector machine achieve promising accuracy and sensitivity in classification. The literature reveals that there is more scope in identifying a patient-specific model in a fully automatic manner.

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