ObjectiveTo establish the prevalence of physical, cognitive and psychiatric
disabilities, associated factors and their relationship with the qualities
of life of intensive care survivors in Brazil.MethodsA prospective multicenter cohort study is currently being conducted at 10
adult medical-surgical intensive care units representative of the 5
Brazilian geopolitical regions. Patients aged ≥ 18 years who are
discharged from the participating intensive care units and stay 72 hours or
more in the intensive care unit for medical or emergency surgery admissions
or 120 hours or more for elective surgery admissions are consecutively
included. Patients are followed up for a period of one year by means of
structured telephone interviews conducted at 3, 6 and 12 months after
discharge from the intensive care unit. The outcomes are functional
dependence, cognitive dysfunction, anxiety and depression symptoms,
posttraumatic stress symptoms, health-related quality of life,
rehospitalization and long-term mortality.DiscussionThe present study has the potential to contribute to current knowledge of the
prevalence and factors associated with postintensive care syndrome among
adult intensive care survivors in Brazil. In addition, an association might
be established between postintensive care syndrome and health-related
quality of life.
Introduction and objectivesLong-term coronavirus disease 2019 (COVID-19) sequelae have become an increasing concern, with persistent dyspnoea and fatigue being the most common and long-lasting symptoms reported. The aim of this study was to evaluate the functional status and respiratory function three months after discharge from an inpatient rehabilitation program.
Materials and methodsThis was a prospective study including post-ICU COVID-19 survivors consecutively admitted to an inpatient and multimodal rehabilitation program in a rehabilitation center. Evaluation of functional status (brief balance evaluation systems test (brief-BESTEST), timed up and go (TUG) test, 1 min sit to stand test (1STST), 6 min walking test (6MWT)); respiratory muscle strength (maximum expiratory pressure (MEP), maximum inspiratory pressure (MIP)); cough effectiveness (peak cough flow (PCF)); and fatigue (fatigue assessment scale (FAS)) were assessed at admission (T0), discharge (T1), and three months after discharge (T2).
ResultsA total of 36 patients were included. Between T1 and T2, there was a significant improvement in MEP (84.47±20.89 vs 97.23±24.63 cmH 2 O, p<0.001), PCF (367.83±117.24 vs 441.33±132.90 L/min, p=0.003), functional capacity (1STST (19.90±6.37 vs 23.13±6.07, p=0.004), and 6MWT (459.25±153.70 vs 500.00±163.74 meters, p=0.003)). No differences were seen in MIP, brief-BESTEST, or TUG. Patients presented a higher median final FAS score at T2 compared to T1: 21.50±5 vs 18.60±2.65, p=0.002.
ConclusionsPost-ICU COVID-19 survivors admitted to an inpatient rehabilitation program maintained a good functional recovery at the three-month follow-up. Despite overall improvement, we found higher scores of FAS, suggesting worse fatigue levels.
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