SKI 0 4TGNectria coccinea produces antibiotics LL-Z1272-p (1 b), -y (ascochlorin) (Za), -8 (3a). and -E (3b) together with a new metabolite for which the name chloronectrin and structure (3c) (based on 3-[5-(3-oxocyclohexyl)pent-2enyl]-5-chloro-orseliinaldehyde) are proposed. In the presence of bromide in place of chloride, N. coccinea produces an analogous 3-(penta-2,4-dienyl) -5-bromo-compound (2c). Several new derivatives in the series are reported.ANTIBIOTICS LL-21272 [a (la), p (1 b) , y (2a), 8 (3a), E (3b), and < (2b)l have been isolated from an unidentified Fusarium sp.l Antibiotic LL-21272 y (2a) (ascochlorin) published data it seems likely that ilicicolin A is identical with antibiotic LL-Z1272-a, B with -PI C with -6, D with -7, and F with -<, though no reference was made in ref. 4 to the work of Ellestad et a1.l We report here the isolation from Nectria coccinea of OR^ 0 R1 R2 R3 R4 a ; C1
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