Three trials were conducted to investigate the superovulatory response of Control Internal Drug Releasing device (CIDR(R)). Forty-six Holstein cows were divided into three treatment groups per trial; CIDR(R) without progesterone (P4) (Control), CIDR(R) containing 1.9 g P4 for 12 days (CIDR(R)-1) and the two CIDRs(R) with P4 replacing with a new CIDR(R) on day 9 of the 12 day insertion period (CIDR(R)-2). Follicle stimulating hormone (FSH) were administered on day 9 up to the time of CIDR(R) removal and additional prostaglandin F2ƒ¿ injections were done on day 11 of the 12 day insertion period. Ovulation rate, recovered and transferable embryos, and P, and estradiol-17ƒÀ (E2) levels in blood plasma were evaluated and compared among the treatment groups. There were no statistical differences on the mean
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