A method for estimating the cholesterol content of the serum low-density lipoprotein fraction (Sf0-20) is presented. The method involves measurements of fasting plasma total cholesterol, triglyceride, and high-density lipoprotein cholesterol concentrations, none of which requires the use of the preparative ultracentrifuge. Comparison of this suggested procedure with the more direct procedure, in which the ultracentrifuge is used, yielded correlation coefficients of .94 to .99, depending on the patient population compared.

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Health was the first systematic treatment of abnorinalities in lipoprotein metabolism and fat transport. In addition to reiterating principles, they reported a simplified technology for measuring lipoproteins thut mu& these new formulations applicable to clinical medicine. Finally, they proposed u syAtem qj' management for the hyperlipoproteinemic phenotypes that was primarily nutritionid. HYPERLIPOPROTEINEMIA Definitions * * *Attention will be paid to practical steps to diagnosis and conservation therapy suitable for the great majority of patients with hyperlipoproteinemia.Reproduced in part with permissionfrom The New England Journal of Medicine.