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Photodynamic therapy today is becoming an important role in the healing of lacerated tissues, since it has therapeutic resources capable of accelerating this process. One treatment option is the clinical phototherapy, and Photodynamic Therapy (PDT) is being widely used. This study aims to evaluate the effect of PDT on the healing of skin wounds in rats. We used a sample of 39 male rats Wistar divided into three groups, a control, a PDT-treated green and red with the last PDT. After 24 hours before the surgical incisions, PDT was used in both groups for 6 minutes and was evaluated in histological level, the inflammatory reaction and the repair process. The results showed that the granulation tissue was more developed in the irradiated group than in the control group and the amount of chronic inflammatory cells (monocytes, macrophages, lymphocytes and plasma cells) predominated with green phototherapy. The epithelialization in the wound margins and scarring with better quality occurred with red PDT (640 nm), which the higher deposition was of collagen. However, phototherapy not collimated of 640 nm (red) resulted in better anti-inflammatory effects. Given these answers with phototherapy not collimated green (525 nm) and red (640 nm), we conclude that the use of these

As hérnias de Spiegel ocorrem por defeito da parede abdominal através da aponeurose spigeliana, entre a linha semilunar e a borda lateral do músculo reto, logo abaixo da linha arqueada de Douglas e, geralmente, acima dos vasos epigástricos superiores. Este defeito pode se estender desde a nona cartilagem costal até a espinha púbica e recebeu esse nome em homenagem ao anatomista belga Adriaan van den Spiegel, após detalhar as estruturas anatômicas envolvidas nesse tipo de hérnia. O seu pequeno e fibroso colo é responsável por estrangulamento em boa parte dos casos. Estas hérnias são de grande interesse para o cirurgião pelos vários diagnósticos diferenciais que se pode levantar. Geralmente, não apresentam sintomas característicos, podendo nem mesmo haver massa evidente à inspeção ou palpação. O objetivo deste trabalho é relatar achados compatíveis com as hérnias de Spiegel, defeitos estes muito raros e com poucos relatos na literatura mundial.

Background: The present work aims to characterize the profile of patients with stroke treat at a hospital located in the Region of the Mata of Minas Gerais, Brazil, considering the findings of the clinical vocal tract, kind of stroke, age and gender of such patients. Methodology: To obtain data, the clinical profile of 133 patients with a clinical or tomography diagnosis of stroke was analyzed, and the results were presented in percentage. For quantitative data average and analysis the tests were done with associations that held χ 2 test, and for significance it was considered p < 0.05. Results: From the total of patients, 63 were women, accounting for 47.4% and the other 52.6% were males. Clinically, they were characterized with the highest percentage for ischemic stroke (89.4%) compared to the hemorrhagic type (10.6%). Most of them were referred for computed tomography (86.5%) and remained hospitalized for an average of 6.496 ± 7.372 days. Similar percentages were obtained in the analysis of the population in question, when considering if they had (54.1%) or not (49.6%) any damage in their speech, language skills or swallowing. There were different types of disabilities in patients with stroke. Men with an average age of 69.8 ± 13.9 presents mostly ischemic stroke, and the majority of patients with stroke had hemiplegia and abnormalities of the vocal tract, dysphasia, and aphasia. While older patients had an ischemic stroke and were presented with left hemiplegia, the younger ones suffered from hemorrhagic strokes that caused a disability characterized as right hemiplegic. Conclusion: Our results show important conclusions regarding the clinical evolution of the vocal tract of patients who suffered strokes during the period of the analysis, being useful 83for better comprehension of how the vocal tract from these patients evolved according to the kind of stroke, sex and age also allowing a contraposition with other future statistics periods available in literature. It can also be pointed out the difficulties in diagnosing the stroke and the concern with the immediate care, but not with its continuance or with its multidisciplinary approach, giving an evident life risk through dysphasia and the increase of permanent damage when there isn't an appropriate work done with the patients.

Mormodica charantia (Curcubitaceae) is a plant with great medicinal potential, also used as an alternative of mosquitoes control as demonstrated by previous studies. We evaluated the larvicidal activity of crude extracts of ethyl acetate, methanol and hexane from flowers and fruits of M. charantia against Aedes aegypti (Culicidae). Flowers and fruits were macerated in methanol, ethyl acetate and hexane. Bioassays were performed with application of the extracts at final concentrations of 1 - 200 µg/mL in the middle of the third instar larvae of A. aegypti (L3). The results showed high toxicity to ethyl acetate extracts from flowers and fruits at concentrations of 200 µg/mL and 100 µg/mL, with 97% and 87% of larvae mortality (L3), respectively. Hexane extract demonstrated low toxicity, while methanol extract exhibited 78% larval mortality. The data suggested that the ethyl acetate extracts of flowers and fruits of M. charantia can effectively contribute to larvicidal activity. In addition, purification of M. charantia extracts may lead to a promising larvicidal activity to control the A. aegypti population.

Objective: To determine the main microbial genotypes and their antimicrobial resistance and susceptibility profile commonly used in the treatment of oncologic patients with febrile neutropenia, carried out through the review of the clinical histories of the patients' medical records at the Hospital do Câncer de Muriaé-Fundação Cristiano Varella. Methods: Quantitative research, determined the susceptibility profile of microorganisms in patients with febrile neutropenia from April 2007 to April 2008 by reviewing clinical histories of patients' medical records at the referred hospital. Results: Of the total of 8 patients evaluated with Gram-negative microorganisms, 50% of the patients were female and 50% were male. Of the 18 patients evaluated with Gram-positive microorganisms 66% were female and 34% male. Gram-positive bacteria are prevalent and cause around 60% of documented bacteremias, although Gram-negative bacteria are more common in febrile neutropenic patientes. Conclusion: Exaggerated use of antimicrobials in hospitalized patients leads to the suppression of drug-sensitive microorganisms from the intestinal flora and promotes the persistence and growth of resistant bacteria. The antibiotic should be used in a curative manner with other therapeutic measures with the determined bacterial infection.

ResumoA mucocele de apêndice ocorre após sua obstrução quando há acúmulo de material mucinoso em seu interior, dilatando assim sua luz. É uma doença rara e geralmente assintomática, sendo na maioria das vezes um achado incidental no momento da laparotomia. Todavia, pode cursar com dor abdominal, alterações de hábito intestinal, massa abdominal, sangramento intestinal, anemia e emagrecimento. O tratamento da mucocele é fundamentalmente cirúrgico e a complicação mais importante é o pseudomixoma peritoneal. Neste trabalho realizamos uma revisão literária e a descrição de dois casos sintomáticos de mucocele benigna do apêndice, diagnosticados e tratados no Hospital Escola Luiz Gioseffi Jannuzzi da Mucocele de apêndice: Relato de dois casos e revisão literária AbstractThe appendix mucocele occurs after its obstruction when there is accumulation of mucinous material in its interior, thus dilating its light. It is a rare and usually asymptomatic disease, most often an incidental finding at the time of laparotomy. However, they may have abdominal pain, changes in bowel habits, abdominal mass, intestinal bleeding, anemia, and weight loss. The treatment of mucocele is primarily surgical and the most important complication is peritoneal pseudomyxoma. In this work we performed a literary review and the description of two symptomatic cases of benign mucocele of the appendix diagnosed and treated at the Hospital Escola Luiz Gioseffi Jannuzzi of the Faculdade de Medicina de Valença (HELGJ-FMV), where the patients evolved well only after the surgical removal of the appendix.

Background: The prostate is the site of problems that have great clinical relevance. Beside this, the alterations in their volume can be divided into benign or malignant pathologies, but of multifactorial cause and there is no examination that alone is reliable for the diagnosis. Despite the evolution of the various methods of diagnostic imaging in the evaluation of pelvic diseases, the diagnosis of prostate cancer still requires histological confirmation obtained by transrectal ultrasound guided biopsy, a procedure that is generally safe and well tolerated by the patients. The most common histological type found in prostate biopsies is adenocarcinoma. Methodology: The objective of this study was to study the values of density of the prostate-specific antigen (DPSA) compared to histopathological results of prostate biopsy, patients attended at the Urology Outpatient Clinic of the Luiz Gioseffi Jannuzzi School Hospital from 1999 to 2007, using Exploratory, retrospective and documentary descriptive study. The sample was divided into groups of patients with adenocarcinoma and patients without adenocarcinoma, who presented only benign prostatic hyperplasia. Results: Of the 251 patients undergoing prostate biopsy, 124 were diagnosed with adenocarcinoma and 127 without adenocarcinoma.How to cite this paper: Brandão,