AstraZeneca, Biosensors, and The Medicines Company.

No abstract

No abstract

Background-As coronary perforation (CP) is a rare but serious complication of percutaneous coronary intervention (PCI) the current evidence base is limited to small series. Using a national PCI database, the incidence, predictors, and outcomes of CP as a complication of PCI were defined. Adjusted odds of adverse outcomes were higher in patients with CP for all major adverse coronary events, including stroke, bleeding, and mortality. Emergency surgery was required in 3% of cases. Predictors of mortality in patients with CP included age, diabetes mellitus, previous myocardial infarction, renal disease, ventilatory support, use of circulatory support, glycoprotein inhibitor use, and stent type. Conclusions-Using a national PCI database for the first time, the incidence, predictors, and outcomes of CP were defined. Methods and Results-DataAlthough CP as a complication of PCI occurred rarely, it was strongly associated with poor outcomes. (Circ Cardiovasc Interv. 2016;9:e003449.