Background: Helicobacter pylori has been strongly associated with chronic gastritis, peptic and duodenal ulcers, and it is a risk factor for gastric cancer. Three major virulence factors of H. pylori have been described: the vacuolating toxin (VacA), the cytotoxin-associated gene product (CagA) and the adhesion protein BabA2. Since considerable geographic diversity in the prevalence of H. pylori virulence factors has been reported, the aim of this work was to establish the H. pylori and vacA, cagA and babA2 gene status in 238 adult patients, from a marginal urban area of Mexico, with chronic gastritis.

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Motion predictions of floating bodies in extreme waves represent a challenging problem in naval hydrodynamics. The solution of the seakeeping problem involves the study of complex non-linear wave-body interactions that require large computational costs. For this reason, over the years, many seakeeping models have been formulated in order to predict ship motions using simplified flow theories, usually based on potential flow theories. Neglecting viscous effects in the wave-induced forces might largely underestimate the energy dissipated by the system. This problem is particularly relevant for unconventional floating bodies at resonance. In these operating conditions, the linear assumption is no longer valid, and conventional boundary element methods, based on potential flow, might predict unrealistic large responses if not corrected with empirical viscous damping coefficients. The application considered in this study is an offshore platform to be operated in a wind farm requiring operability even in extreme meteorological conditions. In this paper, we compare heave and pitch response amplitude operators predicted for an offshore platform using three different seakeeping models of increasing complexity, namely, a frequency-domain boundary element method (BEM), a partly nonlinear time domain BEM, and a non-linear viscous model based on the solution of the unsteady Reynolds-averaged Navier–Stokes (URANS) equations. Results are critically compared in terms of accuracy, applicability, and computational costs.