Amyloidosis is characterized by the deposition of extracellular protein material, amyloid, in various organs.The clinical and imaging features of the disease are often nonspecific and a tissue biopsy is often required. We present the case of a 64-year-old man with biopsy proven amyloidosis of the liver. The patient presented with non-specific clinical symptoms. Routine imaging showed hepatomegaly with heterogeneous enhancement, and several large nodular space occupying lesions, mimicking neoplasm. MR elastography revealed an extremely stiff liver. Amyloidosis presenting as multiple nodular masses on the background of diffuse infiltrative pattern or demonstration of extreme stiffness in hepatic amyloidosis on MR elastography have not been described previously.
A 56-year-old man presented to the Accident and Emergency Department with severe right-sided pleuritic chest pain of sudden onset since the previous night. There was exacerbation of pain on movement, with associated shortness of breath, and a mild fever. He had a history of air travel of five hours' duration ten days prior to presentation. A chest radiograph (Fig. 1a) was done, followed by computed tomography pulmonary angiography (CTPA) (Fig. 2). The plasma D-dimer level was raised at 5.28 mg/L fibrinogen equivalent units (normal < 0.55 mg/L).Comparison was made with a chest radiograph (Fig. 1b)
A 44-year-old man presented with breathlessness and episodes of palpitations for the last one year. The imaging diagnosis of cardiac sarcoidosis was made based on chest radiography and cardiac magnetic resonance (MR) imaging findings, and was further confirmed by biopsy. Cardiac sarcoidosis is an uncommon entity, yet is potentially fatal with nonspecific clinical manifestations, including sudden cardiac death. Hence, it is important to diagnose and treat this entity at an early stage to improve morbidity and mortality. Cardiac MR imaging plays a pivotal role in facilitating diagnosis and monitoring therapeutic response. We describe the MR imaging features of cardiac sarcoidosis and discuss imaging features of other cardiomyopathies that may mimic cardiac sarcoidosis.
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