Abstract. Kidney segmentation in 3D CT images allows extracting useful information for nephrologists. For practical use in clinical routine, such an algorithm should be fast, automatic and robust to contrast-agent enhancement and fields of view. By combining and refining state-of-theart techniques (random forests and template deformation), we demonstrate the possibility of building an algorithm that meets these requirements. Kidneys are localized with random forests following a coarseto-fine strategy. Their initial positions detected with global contextual information are refined with a cascade of local regression forests. A classification forest is then used to obtain a probabilistic segmentation of both kidneys. The final segmentation is performed with an implicit template deformation algorithm driven by these kidney probability maps. Our method has been validated on a highly heterogeneous database of 233 CT scans from 89 patients. 80 % of the kidneys were accurately detected and segmented (Dice coefficient > 0.90) in a few seconds per volume.
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