The T+R protocol evaluated in this study applied to a significant proportion of patients presenting to EMS with SVT. Risk of re-presentation following T+R was low, and paramedic protocol adherence was reasonable. T+R appears to be a viable option for uncomplicated SVT in the prehospital setting.
and/or their parents, the number of pharmacies consulted and reasons for changing pharmacies, delays in obtaining compounded drugs and reasons for the delays, the number of missed doses and potential issues identified with the dispensed compounded drug when compared with the discharge prescription and published formulations. RESULTS: Seventy-one patients with a median age of 6.9 months were surveyed regarding 99 compounded drugs corresponding to 34 different oral compounded drugs. According to the parents, doses of the compounded drugs were provided at hospital discharge for 90 compounded drugs (median 7 days of treatment; IQR 4) and hospital pharmacists contacted the retail pharmacists before discharge for 69 compounded drugs. Out of 314 potential issues identified, 252 involved actual or potential consequences and were therefore considered as issues. Nine involved major and 243 minor actual or potential consequences. One hundred and thirteen (113) of the 252 issues were reported by parents and 139 by the research team. Although any dosage form of compounded drug was eligible for this study, all the recruited compounded drugs were either oral suspensions or oral solutions. CONCLUSION: This study identifies a significant number of compounded-related issues. It suggests that current practice standards are insufficient and action should be taken to improve the use and dispensing of compounded drugs, especially with an aim toward ensuring patient safety.
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