Background:The current 2019 novel coronavirus outbreak is rapidly evolving. YouTube has been recognized as a popular source of information in previous disease outbreaks. We analysed the content on YouTube about n-CoV in English and Mandarin languages. MethodsYouTube was searched using the terms '2019 novel coronavirus', 'Wuhan virus' and '武汉病毒' (Mandarin for Wuhan virus) on 1 st and 2 nd February 2020. First 50 videos in each group were analyzed. Videos in other languages, duplicate videos, those without an audio and duration >15 mins were excluded .72 videos in English and 42 in Mandarin were reviewed . 2 reviewers classified the videos as useful, misleading or news based on pre specified criterion. Inter-observer agreement was evaluated with kappa coefficient. Modified DISCERN index for reliability and medical information and content index (MICI) score were used for content analysis .Results . These videos attracted cumulative 21,288,856 views. 67% of English and 50 % Mandarin videos had useful information. The viewership of misleading Mandarin videos was higher than the useful ones. WHO accounted for only 4% of useful videos. Mean DISCERN score for reliability was 3.12/5 and 3.25/5 for English and Mandarin videos respectively.Mean cumulative MICI score of useful videos was low (6.71/25 for English and 6.28/25 for Mandarin).Conclusions YouTube viewership during 2019 n-CoV outbreak is higher than previous outbreaks. The medical content of videos is suboptimal International health agencies are

Background and Aim A preemptive transjugular intrahepatic portosystemic shunt (p‐TIPSS) after acute variceal bleeding (AVB) is advocated. However, when compared with the current standard of care, the survival benefit of p‐TIPSS is questionable. We performed a systematic review, meta‐analysis, and trial sequential analysis of randomized control trials (RCTs) to assess the survival benefit of p‐TIPSS in patients with cirrhosis and AVB. Methods Comprehensive literature search of three bibliographic databases (MEDLINE, Embase, and Cochrane) was conducted from inception till May 2021. All study types evaluating the survival benefit of p‐TIPSS in AVB were considered for inclusion. The relative risk (RR) of mortality and rebleeding at 6 weeks and mortality at 1 year with a random‐effects model was computed. Trial sequential analysis was performed for the primary outcome of 6‐week mortality. Results A total of nine studies (four RCTs and five cohort studies) comprising 2861 patients with AVB were included. The overall pooled risks of mortality at 6 weeks and 1 year were 17.9% (95% confidence interval [CI]: 16.5–19.3%) and 26.7% (95% CI: 25.0–28.3%), respectively. Although p‐TIPSS was associated with lower 6‐week rebleeding risk (RR = 0.20; 95% CI = 0.13–0.29, I2 = 0%), data from pooled RCTs showed no significant difference in mortality at 6 weeks (RR = 0.33; 95% CI = 0.08–1.36, I2 = 63%) or at 1 year (RR = 0.76; 95% CI = 0.51–1.14, I2 = 30%). Using trial sequential analysis, required sample size to detect a 20% relative risk reduction in mortality at 6 weeks with p‐TIPSS was estimated to be 6317, which is beyond the total number of patients available for analysis. Conclusions This meta‐analysis found that the available data from RCTs are insufficient to confer 6‐week mortality benefit with p‐TIPSS compared with standard of care; thus, adequately powered RCTs are required.

Stingray injuries are usually reported from coastal regions. The injury is caused by the tail spine of the stingray, which can penetrate deep into the soft tissues, and the venom in the tail can cause extensive tissue damage. Imaging plays a very important role in patients with stingray injuries, especially to detect the presence of retained foreign bodies and its complications. We present three cases of stingray injuries to the extremities, with a special emphasis on radiographic findings. Embedded foreign bodies that were radiographically visualized were removed in two of the patients (one patient was discharged at request and was lost to follow-up). We also discuss the types of injuries, clinical presentation, importance of imaging and management considerations in stingray injuries.

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Introduction: In the present study, we aimed to assess whether normal saline injection for sealing the biopsy track is useful in reducing the incidence of pneumothorax after computed tomography (CT)-guided percutaneous transthoracic lung biopsy (PTLB). Methods: We retrospectively compared the incidence of pneumothorax in 100 consecutive biopsies (n = 100, group A) that had injection of saline along the track, with historical cohort of same number of consecutive patients who underwent PTLB without injection of saline along the needle track (n = 100, group B). CT-guided biopsies were performed by coaxial technique and 1-3 ml of saline was injected along the tract. Patient characteristics, lesion size, location and other baseline parameters were compared. Incidence of pneumothorax and number of patients who underwent catheter drainage of pneumothorax was compared in both groups. Results: Baseline characteristics were comparable in both groups. Track sealing with saline was successful in all patients. Pneumothorax rate was 46% for patients in group B and 32% in group A (P < 0.05). Seven patients (7%) had insertion of chest drain for pneumothorax in the group B and only 1% in the group A (P < 0.05). No mortality was observed in both groups. No complications were observed in any of the patients due to saline injection. Conclusion: Track sealing with saline is a simple and safe technique which significantly reduces the incidence of pneumothorax and chest tube insertion after PTLB.