Lucio’s phenomenon is an uncommon reaction characterized by severe necrotizing
cutaneous lesions that occurs in patients with Lucio’s leprosy and lepromatous
leprosy. It is considered by some authors as a variant of type 2 or 3 reaction.
Death can occur because of blood dyscrasia or sepsis. Precipitating factors
include infections, drugs and pregnancy. We report a 31-year-old female patient
exhibiting both clinical and histopathological features of lepromatous leprosy
and Lucio’s phenomenon presenting favorable response to treatment. We complement
our report with a literature review of the Brazilian cases of Lucio’s phenomenon
published in Portuguese and English.
There are many alternatives to treat vitiligo, including surgical procedures, which
are recommended for patients resistant to other therapies. The
melanocyte/keratinocyte transplantation consists in the separation of epidermal cells
obtained from a donor site and spreading these cells on the depigmented and
dermabraded recipient area. Two patients were submitted to transplantation, showing
more than 70% repigmentation in the treated areas after four months, both with
excellent degree of satisfaction. The method requires some laboratory skills, but
represents a simple and safe procedure.
Angiosarcoma is a rare and aggressive tumor with high rates of metastasis and
relapse. It shows a particular predilection for the skin and superficial soft
tissues. We report three distinct and typical cases of angiosarcoma that were
diagnosed in a single dermatology clinic over the course of less than a year: i)
Angiosarcoma in lower limb affected by chronic lymphedema, featuring
Stewart-Treves syndrome; ii) a case of the most common type of angiosarcoma
loated in the scalp and face of elderly man and; iii) a skin Angiosarcoma in
previously irradiated breast. All lesions presented characteristic
histopathological findings: irregular vascular proliferation that dissects the
collagen bundles with atypical endothelial nuclei projection toward the
lumen.
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