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Matthews JB, Basu MK. Plasma cell lesions within the oral tissues: Immunoperoxidase staining of routinely fixed and processed tissue. Oral Surg (in press). 3 Straus W. Imidazole increases the sensitivity of the cytochemical reaction for peroxidase with diaminobenzidine at neutral pH. J Histochem Cytochem 1982;30:491-3. 14 Matthews JB, Mason GI. Immunoglobulin producing cells in human periapical granulomas. Br J Oral Surg (in press). 5 Matthews JB, Jefferis R. The effects of chemical modification on the antigenicity of a human kappa Bence Jones protein. Immunochemistry 1977;14:799-807. 16 Jefferis R, Matthews JB, Bayley PM. Studies of human IgD myeloma proteins. Conformational changes induced in the Fc fragment on heating or exposure to acid pH. Immunochemistrv 1978;15:19-25.

As a method of increasing supplies of varicella-zoster immunoglobulin, semi-automated screening of blood donors for high titre complement-fixing antibody was initiated. This was compared with the previously used method of donor selection based on a history of varicella or zoster in the past 6 months. About one-third of the "history" donors had titres of greater than or equal to 1 in 64 and generally these levels declined rapidly. In contrast, although only 1.1% of donors in random screening had antibody titres greater than or equal to 1 in 64, these levels usually remained high during repeated donation, enabling the production of pools entirely composed of high titre plasma packs.

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