Gamma-ray bursts are the strongest explosions in the Universe since the Big Bang, believed to be produced either in forming black holes at the end of massive star evolution [1, 2, 3] or merging of compact objects [4]. Spectral and timing properties of gamma-ray bursts suggest that the observed bright gamma-rays are produced in the most relativistic jets in the Universe [4]; however, the physical properties, especially the structure and magnetic topologies in the jets are still not well known, despite several decades of studies. It is widely believed that precise measurements of the polarization properties of gamma-ray bursts should provide crucial information on the highly relativistic jets [5]. As a result there have been many reports of gamma-ray burst polarization measurements with diverse results, see [1], however many such measurements suffered from substantial uncertainties, mostly systematic [7, and references therein]. After the first successful measurements by the GAP and COSI instruments [2, 3, 4], here we report a statistically meaningful sample of precise polarization measurements, obtained with the dedicated gamma-ray burst polarimeter, POLAR onboard China's Tiangong-2 spacelab. Our results suggest that the gamma-ray emission is at most polarized at a level lower than some popular models have predicted; although our results also show intrapulse evolution of the polarization angle. This indicates that the low polarization degrees could be due to an evolving polarization angle during a gamma-ray burst.POLAR is a dedicated Gamma-ray Burst (GRB) polarization detection experiment onboard China's Tiangong-2 spacelab [11], launched on Sept. 15th, 2016 and stopped operation on March 31, 2017. POLAR detected 55 GRBs with high significance. In order to make statistically significant GRB polarization measurements and yet with negligible systematic errors, we select a subsample of five GRBs for detailed analysis of their polarization properties; please refer to the supplementary information (SI) for the sample selection criteria and the properties of the five selected GRBs. We employ a straight forward χ 2 based analysis, similar to that successfully employed in [4], to study the polarization properties of the five GRBs, while a Bayesian method is employed to accurately determine the credible regions of the measurements. The studies rely on extensive ground and in-orbit calibration data and Monte-Carlo simulations matching the calibration data [12, 13]. Please refer to the methods section for details of the methodology and analysis.In Figure 1, we show the measured modulation curves of the five GRBs integrated over the whole GRB duration, together with the best fitting simulated modulation curves from linear polarization and fitting residuals. All fittings are statistically acceptable with no significant systematic deviations. In Figure 2, we show the 2-D posterior distributions of the five GRBs, i.e., the posterior probability as functions of both polarization angle (PA) and degree (PD). Clearly the measured P...

A new preclinical PET system based on dSiPMs, called DigiPET, is presented. The system is based on thin monolithic scintillation crystals and exhibits superior spatial resolution at low-cost compared to systems based on pixelated crystals. Current dedicated small-rodent PET scanners have a spatial resolution in the order of 1 mm. Most of them have a large footprint, requiring considerable laboratory space. For rodent brain imaging, a PET scanner with sub-millimeter resolution is desired. To achieve this, crystals with a pixel pitch down to 0.5 mm have been used. However, fine pixels are difficult to produce and will render systems expensive. In this work, we present the first results with a high-resolution preclinical PET scanner based on thin monolithic scintillators and a large solid angle. The design is dedicated to rat-brain imaging and therefore has a very compact geometry. Four detectors were placed in a square arrangement with a distance of 34.5 mm between two opposing detector modules, defining a field of view (FOV) of 32 × 32 × 32 mm(3). Each detector consists of a thin monolithic LYSO crystal of 32 × 32 × 2 mm(3) optically coupled to a digital silicon photomultiplier (dSiPM). Event positioning within each detector was obtained using the maximum likelihood estimation (MLE) method. To evaluate the system performance, we measured the energy resolution, coincidence resolving time (CRT), sensitivity and spatial resolution. The image quality was evaluated by acquiring a hot-rod phantom filled with (18)F-FDG and a rat head one hour after an (18)F-FDG injection. The MLE yielded an average intrinsic spatial resolution on the detector of 0.54 mm FWHM. We obtained a CRT of 680 ps and an energy resolution of 18% FWHM at 511 keV. The sensitivity and spatial resolution obtained at the center of the FOV were 6.0 cps kBq(-1) and 0.7 mm, respectively. In the reconstructed images of the hot-rod phantom, hot rods down to 0.7 mm can be discriminated. In conclusion, a compact PET scanner was built using dSiPM technology and thin monolithic LYSO crystals. Excellent spatial resolution and acceptable sensitivity were demonstrated. Promising results were also obtained in a hot-rod phantom and in rat-brain imaging.

The mouse model is widely used in a vast range of biomedical and preclinical studies. Thanks to the ability to detect and quantify biological processes at the molecular level in vivo, PET has become a well-established tool in these investigations. However, the need to visualize and quantify radiopharmaceuticals in anatomic structures of millimetre or less requires good spatial resolution and sensitivity from small-animal PET imaging systems.In previous work we have presented a proof-of-concept of a dedicated high-resolution small-animal PET scanner based on thin monolithic scintillator crystals and Digital Photon Counter photosensor. The combination of thin monolithic crystals and MLE positioning algorithm resulted in an excellent spatial resolution of 0.7 mm uniform in the entire field of view (FOV). However, the limitation of the scanner was its low sensitivity due to small thickness of the lutetium-yttrium oxyorthosilicate (LYSO) crystals (2 mm).Here we present an improved detector design for a small-animal PET system that simultaneously achieves higher sensitivity and sustains a sub-millimetre spatial resolution. The proposed detector consists of a 5 mm thick monolithic LYSO crystal optically coupled to a Digital Photon Counter. Mean nearest neighbour (MNN) positioning combined with depth of interaction (DOI) decoding was employed to achieve sub-millimetre spatial resolution. To evaluate detector performance the intrinsic spatial resolution, energy resolution and coincidence resolving time (CRT) were measured. The average intrinsic spatial resolution of the detector was 0.60 mm full-width-at-half-maximum (FWHM). A DOI resolution of 1.66 mm was achieved. The energy resolution was 23% FWHM at 511 keV and CRT of 529 ps were measured. The improved detector design overcomes the sensitivity limitation of the previous design by increasing the nominal sensitivity of the detector block and retains an excellent intrinsic spatial resolution.

We propose to perform a continuously scanning all-sky survey from 200 keV to 80 MeV achieving a sensitivity which is better by a factor of 40 or more compared to the previous missions in this energy range. The Gamma-Ray Imaging, Polarimetry and Spectroscopy (GRIPS) mission addresses fundamental questions in ESA's Cosmic Vision plan. Among the major themes of the strategic plan, GRIPS has its focus on the evolving, violent Universe, exploring a unique energy window. We propose to investigate $\gamma$-ray bursts and blazars, the mechanisms behind supernova explosions, nucleosynthesis and spallation, the enigmatic origin of positrons in our Galaxy, and the nature of radiation processes and particle acceleration in extreme cosmic sources including pulsars and magnetars. The natural energy scale for these non-thermal processes is of the order of MeV. Although they can be partially and indirectly studied using other methods, only the proposed GRIPS measurements will provide direct access to their primary photons. GRIPS will be a driver for the study of transient sources in the era of neutrino and gravitational wave observatories such as IceCUBE and LISA, establishing a new type of diagnostics in relativistic and nuclear astrophysics. This will support extrapolations to investigate star formation, galaxy evolution, and black hole formation at high redshifts.Comment: to appear in Exp. Astron., special vol. on M3-Call of ESA's Cosmic Vision 2010; 25 p., 25 figs; see also www.grips-mission.e