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As part of the ITER Design Review, the physics requirements were reviewed and as appropriate updated. The focus of this paper will be on recent work affecting the ITER design with special emphasis on topics affecting near-term procurement arrangements. This paper will describe results on: design sensitivity studies, poloidal field coil requirements, vertical stability, effect of toroidal field ripple on thermal confinement, heat load requirements for plasma-facing components, edge localized modes control, resistive wall mode control, disruptions and disruption mitigation.