A721 physiotherapist. Finally, 6.2% of patients were hospitalized for MS (average duration of 3.6 days). Comparing MS patients to a matched control group resulted in estimating the excess direct cost attributable to MS to 9,659€ (±6,059€) in 2014 (average annual growth rate: 3.9% over 2012-2014). Main cost drivers were pharmaceuticals (49%), hospital care (22.9%), nursing care (7.8%), medical devices (6.5%) and physiotherapy care (6%). ConClusions: The direct burden of MS was evaluated to 965 € million in 2014 in France mainly due to disease-modifying therapies. Such burden highlights the importance of developing cost-effective drugs.
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