The diuretic activity of bumetanide has been studied in 16 Glasgow, London, and Sheffield, England Department of Medicine, Western Infirmary, Glasgow, Department of Therapeutics, Westminister Hospital, London, and Department of Pharmacology and Therapeutics, Royal Infirmary, Sheffield Bumetanide (3-n-butylamino-4-phenoxy-5-sulfamoylbenzoic acid, Brinex) is a derivative of metanilamide that displays potent diuretic activity on oral administration
A model for coronary collateral vessel development is presented for the pig heart. Chronic stenosis of the left anterior descending coronary artery results in collateral development to functional myocardium with limited mechanical reserve.
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