Studies have shown the participation of minerals in mechanisms involved in the pathogenesis of insulin resistance. Zinc, in particular, seems to play an important role in the secretion and action of this hormone. Therefore, the aim of this review is to understand the role of zinc in increasing insulin sensitivity. We conducted a search of articles published in the PubMed and ScienceDirect database selected from March 2016 to February 2018, using the keywords "zinc," "insulin," "insulin resistance," "insulin sensitivity," and "supplementation." Following the eligibility criteria were selected 53 articles. The scientific evidences presented in this review show the importance of zinc and their carrier proteins in the synthesis and secretion of insulin, as well as in the signaling pathway of action of this hormone. Zinc deficiency is associated with glucose intolerance and insulin resistance; however, the effectiveness of the intervention with the zinc supplementation is still inconclusive.
Breast cancer is a disease of high mortality, characterized by the progressive accumulation of mutations that contribute to the uncontrolled development of breast tissue cells. Literature shows that disturbances in mineral homeostasis, such as magnesium, may interfere with tumor progression. The objective of this study is to provide updated information about magnesium's role in the pathogenesis of breast cancer. A review of literature was carried out from a search for articles in the PubMed and CAPES Periodicals databases published between 1995 and 2016 with the cross-references of the descriptors "magnesium," "breast neoplasms," and "oxidative stress" and the corresponding words in Portuguese. We included studies on the metabolism and bioavailability of magnesium and studies related to breast cancer and excluded articles in which only the abstract was available, dissertations, theses, articles involving adjuvant and/or neoadjuvant therapies, and supplementation of minerals in breast cancer patients. Magnesium is a mineral that participates in the metabolism of various nutrients and nucleic acids. In the presence of breast cancer, neoplastic cells increase the expression of magnesium transport channels, which raises the intracellular concentration of the mineral, contributing to tumor growth through its function of increasing energy demand. The data obtained in this review illustrates the influence of magnesium on the progression of breast cancer. However, the existing data are scarce and inconsistent, which demonstrates a need for further studies on the subject with a goal to have better control of the disease.
Introduction: Aging is a physiological process, which is characterized by successive wear and tear. However, it has been found that physical activity delays and/or minimizes those effects. The Pilates method proposes aphysical conditioning of the entire body.The Pilates method of body conditioning has low-intensity and low-impact exercise programs associated to long-standing exercise sessions. Objectives: The study aims to analyze and compare the functionality and flexibility of both adult women and elderly women groups before and after performing Pilates exercises on the ground. Patients and Methods: The current study is a clinical trial involving 14 sedentary women who attend dance groups incommunity gyms in the city of Teresina -Piaui State. They were divided into two groups: the adult women group (AW) and the elderly women group (EW). Both groups have performed a training program, including 12 sessions of Pilates exercises on the ground within 4 weeks, 3 times per week, 50 minutes long. The exercises took place in a public square they used to attend. At the beginning and at the end of t study, all volunteers were tested through the protocol developed by the Latin-American Development to the Maturity Group (GDLAM'S Protocol) and the distance hand-ground test. Data were analyzedusing the Kolmogorov-Smirnov test andanalysis of variance (ANOVA) for repeated measurements and effect size. A P value < 0,05 was considered as statistically significant. Results: According to the functional autonomy classification, both adult women and elderly women showed improvement ranging from weak to regular regarding the levels of physical activity. Conclusion: This study concludes that Pilates exercises performed in 12 sessions promoted improvement inthe functional autonomy and retained the flexibility in bothgroups of adult women and elderly women.Descriptors: Exercise; Physical Therapy Specialty; Aging.
IntroduçãoO envelhecimento é caracterizado por um conjunto de alterações fisiológicas desfavoráveis que prejudicam principalmente aspectos relacionados ao desempenho (1)(2)(3) . Um estilo de vida saudável, com uma alimentação adequada e exercícios físicos regulares estão associados à melhora da qualidade de vida e diminuição da incidência de doenças crônicas (4) . A participação de adultas 22(3) 53-57
Tais achados foram evidenciados que os sintomas do climatério podem reduzi significativamente na qualidade de vida sexual como: ressecamento vaginal, redução da libido, fogacho e acesso a informação. Tais alterações favorecem disfunções sexuais e conflito conjugais, refletindo também em variações no estado psicológico. Para os achados concludentes, foi possível identificar poucos estudos sobre atemáticas, dessa forma, mostrar a necessidade e relevância de estudos futuros sobre a temática.
Com o crescimento da população idosa, houve um aumento nos casos de doenças crônicas, dentre elas o câncer de próstata. Dentre os tratamentos, a cirurgia pode ter efeitos secundários que influenciam na qualidade de vida sexual. Com isso, torna-se necessário investigar esses pacientes. O objetivo do estudo foi analisar a qualidade de vida sexual em pacientes que se submeteram a prostatectomia. O estudo se refere a uma revisão integrativa da literatura, no qual os critérios de inserção foram: artigos na íntegra que ressaltaram a qualidade de vida sexual em pacientes pós-prostatectomia publicados entre 2015 até 2020, nas bases de dados da SCIELO e LILACS. Para a construção dos achados foram selecionados 7 artigos por atenderem os criterios de elegibilidade. Tais evidências apontam que a redução da libido e a disfunção erétil podem contribuir para má qualidade de vida sexual. Informações sobre a chance de recuperação de ereções naturais dos pacientes foram frequentemente repassadas a eles para que, junto aos seus parceiros sexuais, para que se permitam encarar e se adequar à esta nova realidade. Ainda que a disfunção erétil tenha elevada prevalência entre homens que realizaram a cirurgia, em alguns casos há déficit de discussão no pré-operatório. Com isso, a qualidade de vida sexual pós prostatectomia é comprometida devido à impactos na sexualidade, repercutindo em diferentes esferas da vida. Ainda é um tema pouco abordado com pacientes e há escassez de evidência sobre o assunto. Este estudo visa abrir espaço para planejamento de mais estudos para melhor beneficiar pacientes pós prostatectomizado.
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