In the present study, antiimplantation activity of methanolic extract of Cordia dichotoma Lam. bark was evaluated. The methanolic extract of bark of Cordia dichotoma showed significant antiimplantation activity. Pretreatment with methanolic extract showed significant inhibition of number of implant site at a dose of 100-mg/kg-body weight. There was no change in ovulation; hence the antiimplantation activity observed in the present study with Cordia dichotoma bark can be attributed largely to its inhibition of number of implants. However, an investigation of the antiimplantation activity showed no increase in body weight or uterine content of blood glucose, cholesterol and triglyceride levels when compared with control group.
Ethyl-2-amino-4-chloro-6-(2, 4, 6 trichloro phenyl amino) pyrimidine-5-carboxylate and ethyl-2-amino 4-chloro-1, 3-dimethyl-6-(phenyl amino)-1,2,3,4 tetrahydro pyrimidine-5-carboxylate derivatives were synthesized through Cyclocondensation and Michel type of addition reaction with the aromatic anilines, guanidine and benzamidines. Synthesized novel derivatives were confirmed by elemental analysis viz., IR, 1HNMR and Mass spectroscopy.These novel derivatives have been screened for Antibacterial, Antifungal and Antiinflammatory activity.
Herbal cosmetics have growing demand on the earth market and are a precious gift of nature. Herbal formulations continuously have attracted gigantic concentration on the grounds that of their good endeavor and comparatively lesser or nil side effect with synthetic medications. Hair loss problem is of great significance to both men and women. Alopecia is the medical term for hair loss or baldness. It is a health condition in which hair is lost from some or all areas of the body, usually from the scalp. Hair loss can be caused due to different reasons, such as genetics, environmental triggers, exposure to chemicals, medicines, nutritional deficiency, extreme stress or long illness etc. This hindrance could be solved by the use of natural medicines obtained from herbs. Various herbs are being used to preclude the hair loss and remorse of hairs. Herbs are starting material for any medicine research. Approximately about 80% residents recommended herbal drugs for their beneficial effects along with fewer side effects as compared synthetic drugs.
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