These results demonstrate that there is sustained reduction in PE-induced MAP responsiveness which accompanies exercise-induced decreases in blood pressure in the Dahl salt-sensitive rat. Thus, decreased alpha-adrenoceptor responsiveness may contribute to the production of PEH.

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Food-intake restriction attenuates the rise in MAP which occurs after aortic coarctation significantly. The antihypertensive effect of food-intake restriction may be mediated via a reduction in sympathetic tone.

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