Abstract| In this paper we summerize the derivation of the size equations, the key to timing closure. Next we present a n umber of problems when applying these equations in practice. The main ones are network generation, discrete libraries, size constraints, and resistive i n terconnect.
Magnetic nanoparticles (MNPs) are widely known as valuable agents for biomedical ap-plications. Yet, for their successful application within cells they need to fulfill a variety of demands such as monodispersity, biocompatibility or sufficient magnetic response. Given these prerequisites, MNPs may be used for remote, non-invasive manipulation, where their spatial redistribution or force response in a magnetic field provides a fine-tunable stimulus to a cell. Here, we investigate the properties of two different MNPs and their suitability for spatio-mechanical manipulations: sem-isynthetic magnetoferritin nanoparticles and fully synthetic nanoflower-shaped iron-oxide nano-particles. Next to characterizing their structure, surface potential and magnetic response, we monitor the MNP performance in a living cell environment using fluorescence microscopy and confirm their biocompatibility. We then demonstrate their capability to spatially redistribute and to respond to magnetic force gradients inside a cell. Our remote manipulation assays present these tailored mag-netic materials as suitable agents for applications in magnetogenetics, biomedicine or nanomaterial research.
Jesus begins his ministry with appeals to Elijah and the widow, making bold and controversial claims about the true beneficiaries of the kingdom of God (Luke 4:25–26; cf. 1 Kgs 17:8–24). Although commentators recognize subsequent allusions to this episode throughout Luke-Acts, these are generally noted in passing and in isolation from each other. This article draws from recent studies that examine “redundant” narrations in the Lukan narrative, applying the same methodology to the phenomenon of the narrator’s repetitive reappropriation of a given OT episode. In examining repeated appeals to the Zarephath account within the Lukan narrative (Luke 4:26; 7:11–17; Acts 9:32–43; 20:7–12; cf. 1 Kgs 17:17–24), it is argued that these passages, when linked together, create a literary arc that spans almost the entirety of Luke-Acts. Viewed as a whole, this arc highlights the unfolding understanding of the true people of God in Lukan theology.
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