BACKGROUND: To examine the impact of different types of sleep deprivation on hippocampal-mediated learning and memory in rats. METHODS: Forty-eight Sprague-Dawley male rats were randomly assigned to 1 of 4 equal-size groups: (1) 12 hours of sleep per day (control). (2) total sleep deprivation (TSD), (3) rapid eye movement (REM) deprivation (RD), and (4) sleep restricted to 4 hours per day (SR). All rats were subjected to swimming training in the Morris water maze (MWM). At the end of the experiments, the rats were decapitated, and hippocampus tissue was analyzed for several neurotransmitters and receptors. RESULTS: The time spent at the target quadrant increased from 20.2 to 30.0 seconds in the control group on the third day of the experiment, whereas corresponding values increased from 20.2 to 21.8 seconds in the TSD group, 22.1 to 25.4 seconds in the RD group, and 21.2 to 32.0 sec in the SR group (p = 0.026). On the seventh day of the experiment, the values decreased to 25.0 seconds in controls, 22.5 in the RD group, and 23.6 in the SR group (p = 0.045). The TSD group demonstrated signifi cant decreases in glutamate and serotonin levels compared with the control group. There was a signifi cant increase in 5-HT2 a receptor expression in all intervention groups compared with the controls. CONCLUSIONS: Our results of glutamate levels and 5-HT2a receptor expression in the hippocampus seem to be primarily involved in sleep and memory regulation (Tab. 2, Fig. 4, Ref. 59). Text in PDF www.elis.sk.

The foundations of a healthy life are laid during youth, and healthy nutrition and regular physical activity are not only two key determinants of health but also two main factors decreasing age-related health risks. Universities are the ideal environments for increasing this awareness and educating university students that constitute the majority of young population on healthy behavioral choices. This study aimed to evaluate the factors affecting the attitudes of the students of the Faculty of Health Sciences (Department of Physiotherapy and Rehabilitation and Department of Nutrition and Dietetics) at a foundation university towards healthy nutrition and physical activity. Methods: The total number of students in the Department of Physiotherapy and Rehabilitation and Department of Nutrition and Dietetics was 467. The study aimed to reach the whole universe and was conducted with 339 students (73%) that consented to participate. Study data were collected via faceto-face surveys that covered the sociodemographic data form, demographic data questions of the modified survey by the University of North Florida on Diet and Exercise and the survey including the Body Image Scale. The study received an approval from the Scientific Researches Ethics Council of the School of Medicine of Trakya University (TÜTF-BAEK 2019/163). Study data were analyzed using SPSS 25.0 program. Significance level was p<0.05. Chi-square analysis was used for group comparisons as the data were categorical variables. Results: While the Cronbach's α coefficient was 0.91 in the original Body Image Scale, it was 0.959 in our study. In addition, while prediction point was 135 in the original scale, it was 134.5 according to our ROC analysis. 49.6% of students stated that they did not exercise; 27.1% of those associated it with "lack of time" while 17.1% cited "lack of willpower". 54% of students considered their diets unhealthy. There was a statistically significant difference between lack of exercise and gender (p<0.05). 81% of females did not exercise at all while 19% of males did not exercise. Among students whose body image perception was below average, the number of those not exercising (n=52) was higher than those exercising (n=36), and this was statistically significant (p<0.05). Conclusions: According to results of this study, university students should be provided with awareness programs on healthy nutrition and exercise to promote healthy lifestyle behaviors.

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