Radikal bebas yang berbahaya jika konsentrasi ROS akan meningkat sehingga akan mengakibatkan stress oksidatif. Stress oksidatif biasanya disebabkan oleh konsentrasi tinggi dari radikal bebas dalam sel dan jaringan yang dapat diinduksi oleh beberapa faktor negatif seperti gamma, UV, radiasi sinar-X, tekanan psiko-emosional dan makanan yang tercemar.Untuk meminimalisir radikal bebas dalam tubuh diperlukan antioksidan alami seperti ekstrak buah kiwi dan ekstrak buah apel. Uji aktivitas antioksidan pada masing- masing ekstrak dilakukan dengan metode DPPH (1,1- difenil-2-pikrihidazil). Hasil menunjukkan bahwa nilai IC50 dari ekstrak buah kiwi lebih rendah daripada IC50 ekstrak buah apel. Hal ini menunjukkan bahwa ekstrak buah kiwi mempunyai aktivitas antioksidan lebih kuat dari ekstrak buah apel. Keyword : Radikal bebas, DPPH, Ekstrak buah kiwi, Ekstrak buah apel Free radicals will be dangerous if the ROS concentration will increase and causes oxidative stress. Oxidative stress is usually caused by high concentrations of free radicals in cells and tissues which can be induced by several negative factors such as gamma, UV, X-ray radiation, psycho-emotional pressure and contaminated food. To minimize free radicals in the body natural antioxidants such as kiwi fruit extract and apple extract. The antioxidant activity test on each extract was carried out by the DPPH method (1,1-diphenyl-2-picrihydazyl). The results showed that IC50 value of kiwi fruit extract was lower than IC50 of apple fruit extract. This shows that kiwi fruit extract has stronger antioxidant activity than apple extract. Keyword : free radicals, DPPH, kiwi fruit extract, apple fruit extract
Herd immunity or herd effect is a phenomenon that occurs in groups of people who are resistant to disease. The purpose of conducting this research is to predict the number of cumulative cases of COVID-19 in Indonesia. Covid-19 cases in Indonesia on April 6, 2020, were 2235 cases spread in 34 Provinces. As many as 2491 cases in Indonesia, there were 192 patients recovered (including those treated, so they have natural antibodies in the end) while the total who died was 209 people. It is assumed that around 13% of the total cases have natural antibodies. This is also the case with SARS-CoV-2 and may explain why some individuals (perhaps those most recently able to recover from seasonal coronavirus infections) have asymptomatic infections. Finally, the theoretical concept of increasing herd immunity in pandemic and epidemic cases in Indonesia which aims to control COVID-19 still needs to be reviewed because it is seen from the mortality data that CFR COVID-19 is predicted to be around 8.39% of the population in Indonesia where the risk of death still available. The best alternative is to do a healthy lifestyle, social distancing, and waiting for the vaccine to be found.
Background.Periapical tooth infection is one of infection problems which often happens such as abscess periapical which is caused by bacteria. The bacteria which can form biofilms is named streptococcus viridans. It is resistant towards an antibacterial agent. Chitosan made of shrimp shells is used as a natural antibiofilms agent for streptococcus viridans. Purpose.To determine the effective concentration of antibiofilms capacity from shrimp shells chitosan towards streptococcus viridans. Method.The research method used in this research is laboratory experimental research. The research design is post-test only controlgroup design. Streptococcus viridans is given vortex until it becomes homogeneous with standard turbidity McFarland of 0.5, than, it is planted inside a microtitter plate using TSB Glu for 5x24 hours. At last, Streptococcus viridans is colored using crystal violet and the picture of biofilms is observed using inverted microscope. Chitosan liquid diluted through various concentration 0.195%, 0.39%, 0.78%, 1.56%, 3.125%, 6.25%, 12.5%, 25%, 50% and 100% are going to be added to the microtitter plate and being incubated for 24 hours. The interpretation of the result on the longitude of the wave through optical density is 570nm. Result.There is a significant difference between the concentration of 100%, 50%, 25%, 12.5%, 6.25%, 3.125%, 1.56%, 0.78%, and 0.39% and the control group. Chitosan’s effective concentration in resisting the biofilms is 50%. The result is determined by statistical analysis. Conclusion.The effective concentration to resist the formation of Streptococcus viridans biofilms using shrimp shells chitosan is 50%.
The results of the 2018 Basic Health Research (Riskesdas) show that 57.6% of the Indonesian population has dental and oral health problems, with the largest proportion being dental caries. This condition also occurs in children, where as many as 93% of early childhood in Indonesia experience dental caries. Dental care is difficult to do during the COVID-19 pandemic, making dental and oral health services prioritized in promotive and preventive efforts. Promotional actions can be taken to increase knowledge and get used to maintaining dental and oral health. Objective: to provide understanding and increase knowledge of dental and oral health for school-age children in Krikilan, Masaran, Sragen. Methods: The activity was carried out at SDN 2 Krikilan, Masaran, Sragen with interactive lecture methods and demonstrations using visual aids in the form of posters and dental models. Gifts in the form of toothbrushes and toothpaste were given after the presentation of the material and evaluation of the results of the counseling. Results: The children understand and can demonstrate how to brush their teeth properly and correctly and are able to explain when to brush their teeth properly. Conclusion: Direct counseling to children with active lecture methods and demonstrations of teaching aids is effective to increase children's knowledge about oral health. ABSTRAK Hasil Riset Kesehatan Dasar (Riskesdas) 2018 menunjukkan bahwa 57,6% penduduk Indonesia mempunyai masalah kesehatan gigi dan mulut dengan proporsi terbesar adalah karies gigi. Kondisi ini juga terjadi pada anak-anak dimana sebanyak 93% anak usia dini di Indonesia mengalami karies gigi. Perawatan gigi sulit dilakukan pada masa pandemi COVID-19 menjadikan layanan kesehatan gigi dan mulut lebih diutamakan pada upaya promotif dan preventif. Tindakan promotif dapat dilakukan untuk meningkatkan pengetahuan dan membiasakan memelihara kesehatan gigi dan mulut. Tujuan: untuk memberikan pemahaman dan meningkatkan pengetahuan kesehatan gigi dan mulut anak usia sekolah di Desa Krikilan, Sragen. Metode: Kegiatan dilakukan di SDN 2 Krikilan, Masaran, Sragen dengan metode ceramah interaktif dan demonstrasi menggunakan alat peraga berupa poster dan model gigi. Pemberian hadiah berupa sikat gigi dan pasta gigi dilakukan setelah acara penyampaian materi dan evaluasi dari hasil penyuluhan. Hasil: Anak - anak memahami dan dapat memperagakan cara menyikat gigi dengan baik dan benar serta mampu menjelaskan waktu sikat gigi yang tepat. Kesimpulan: Penyuluhan secara langsung pada anak dengan metode ceramah aktif dan demonstrasi alat peraga efektif untuk meningkatkan pengetahuan anak tentang kesehatan gigi dan mulut.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
hi@scite.ai
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.