Highlights d Deletion of Caspase-9 in hair follicle stem cells delays the apoptotic cascade d Apoptotic hair follicle stem cells release Wnt3 and instruct proliferation d A caspase-3/Dusp8/p38 module is responsible for Wnt3 induction in apoptotic cells d Casp-9 fl/fl mice display accelerated wound repair and de novo hair follicle neogenesis.
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