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A PSA value >1 ng/mL before salvage and a biochemical progression during RT were both independently correlated with worse bRFS after SRT. By using erMRI to select patients who are most likely expected to benefit from dose-escalated SRT protocols, this dose-adapted SRT approach was associated with good biochemical control and outcome, serving as a hypothesis-generating basis for further prospective trials aimed at improving the therapeutic ratio in the salvage setting.

The outbreak of the novel coronavirus disease-19 (COVID-19) has rapidly and drastically impacted worldwide the healthcare system. Despite an increasing number of recommendations becoming available in the last two months, measures adopted in radiationoncology departments to overcome this situation are rapidly changing and may differ largely based on institutional and national practices.We conducted a national survey of all radiation oncology centers in Switzerland to better understand the early impact of the COVID-19 pandemic on our discipline. MethodsA 53-questions online survey was finalized on April 6th, 2020 using available recommendations [1-8] and distributed by email on April 07th, 2020 to the representatives of the 30 Swiss radiation