MEDICAJLJOURNAL solution-for example, 0 5 ,ug./ml. It seems probable that the outstanding prophylactic effectiveness of silver nitrate compresses is due to the high concentration of silver ions present in the dressings for a short while after each replenishment of silver nitrate solution.The tests on Ps. aeruginosa showed that the lowest concentration of silver ions associated with bactericidal action was considerably higher than that associated with bacteriostasis. This difference can probably be ascribed in part to the shorter exposure of bacteria in the tests for bactericidal action; it is possible, too, that a higher concentration of silver ions is required for killing than for inhibition of the bacteria. REFERENCES Cason, J. S., Jackson, D. M., Lowbury, E. J. L., and Ricketts, C. R. (1966 British Medical_Journal, 1970, 2, 446-449 Summary: Forty-eight patients with anxiety states were treated with oxazepam (Serenid-D), which was administered in tablets of three different colours-red, yeliow, and green. Every patient received one week's treatment with each colour, according to a random programme. A latin square design was used to ensure complete balance between the colours and between the weeks. The patients' symptoms were categorized and then assessed by both weekly physicians' ratings and daily self-rating, which showed close agreement. Colour preference was shown on both these scales in that symptoms of anxiety were most improved with green, whereas depressive symptoms appeared to respond best to yellow. Such colour preferences, however, did not reach levels of statistical significance, except for phobias as rated on the physicians' assessment.The results indicate that colour may play a part in the response to a drug.
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