This review describes applications of light in photonic therapies, especially photodynamic therapy (PDT) which involves the combination of light, photosensitizer and oxygen. Relevant examples of porphyrins, chlorins and phthalocyanines were chosen and are presented, among the commercially available and presently under study photosensitizers of interest at the moment. Our objective is not to be exhaustive, but discuss the general ideas on PDT and photosensitizers as they demonstrate interaction with light and the human body.
The synthesis of the new dye 1,6-methano[10]annulenecyanine is described. For this purpose, the 3,4-dicyano-1,6-methano[10]annulene and 3,4-carboxyimide-1,6-methano[10]annulene buildings blocks were synthesized in six to eight steps. In both cases, these building blocks were then cyclotetramerized to furnish a new Zn(II)-1,6-methano[10]annulenecyanine which presents a strong red-shifted absorption band at 800 nm and high solubility in common organic solvents.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.