Background: Griscelli syndrome type-2 (GS2) is characterized by cutaneous hypopigmentation, immunodeficiency, and hemo-phagocytic lympho-histiocytosis. Primary neurological presentation is rare. Case Report: We hereby report 13 year old girl who presented with cutaneous hypopigmentation, clinical and radiological evidence of neurologic involvement unaccompanied by other features of hemo-phagocytosis. Electron microscopy of hair shaft and skin biopsy established the diagnosis of Griscelli syndrome. Conclusion: Neurologic manifestations in Griscelli syndrome may occur in isolation without the more common hemophagoctic-lymphohistiocytosis.
BAckgrOundBreast milk is the ideal food for infant and its role for the newborn growth, development and immunity is universally recognized. The World Health Organization recommends exclusive breastfeeding for the first six months of life "to achieve optimal growth, development and health" [1,2]. Unfortunately, exclusive breastfeeding rate is only 28% at 4-5 months of age [3]. There are numerous factors behind discontinuation of breast feeding, ranging from those related to the newborn (prematurity, sickness), mother (sickness, depression) or social (working mother, myths) [1].
scite is a Brooklyn-based startup that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.