Background
Little is known about the epidemiology of lymphomas occurring in oral and para-oral sites, especially in developing countries such as Egypt. Hence, the aim of this study was to describe the frequency and time trends of oral and para-oral lymphomas in Cairo governorate from 2010 to 2019, with forecasting to 2030, and to examine relations between age, gender, site and type of lymphoma.
Methods
Histopathological reports of patients diagnosed with oral and para-oral lymphomas from 2010 to 2019 were retrospectively retrieved from archives of six different centers in Cairo governorate. Data regarding age, gender and site was collected and associations between types of lymphoma and these variables were detected using appropriate statistical methods. The significance level was set at p ≤ 0.05. Time series analysis was used to determine the trend of lymphoma frequency within 10 years of the study and to predict frequency until 2030.
Results
Lymphomas constituted 2.86% of oral and para-oral lesions. Non-Hodgkin lymphoma was more common than Hodgkin lymphoma. Patients with non-Hodgkin lymphoma showed a higher median age than patients with Hodgkin lymphoma (p = 0.001). Non-Hodgkin lymphoma was more prone to occur intra-orally (p = 0.014). No statistical significance was observed in gender distribution between Hodgkin and non-Hodgkin lymphoma. Even though no specific time trend was observed from 2010 to 2019, forecasting for frequency of lymphomas through 10 years (2020 to 2030) showed a predicted increase.
Conclusions
The findings of this study were consistent with majority of other studies held in various geographic regions. The study revealed that frequency of oral and para-oral lymphomas in Cairo governorate is expected to rise; hence, oral pathologists should be more clinically suspicious and expect to encounter these lesions more in their practice within the upcoming years.
Background: guided bone regeneration (GBR) is considered a predictable method when used to treat 3D alveolar defects prior to implant placement. The aim of this study was to compare the histomorphometric outcomes following GBR of 3D bone defects in the maxilla using a 3D patient specific milled titanium mesh vs. a 3D patient specific, milled PEEK meshes.Material and methods: split mouth study was conducted on 8 patients (16 alveolar ridge) suffering from 3D maxillary alveolar defects. GBR was performed using an equal mixture of autogenous and xenogenic bone grafts loaded on either patient specific milled Titanium mesh (control group) or patient specific milled PEEK mesh (test group). Implant placement and core biopsied was carried out 6 months following alveolar ridge augmentation.Results: Wound healing was uneventful for all cases except one patient in each group were the meshes were exposed. There was a statistically significant difference between both groups (P value = 0.000).
Conclusion:These results showed that patient specific milled Titanium meshes provide a superior osteoinductive and osteoconductive properties compared to milled PEEK meshes. yet further studies using larger sample size is needed.
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