IVietnam, little attention is being paid to the management and treatment of septic tank sludge to take advantage of the number of nutrients in this available resource. This paper presents the potentials and performance of the compost production on the mixing of septic tank sludge and agricultural residues as coffee husk, coconut husk, peat. It added supplementary by 5% bioproducts of Trichoderma sp and 30 ml of molasses in 45days. The results showed the highest quality compost, being mixes of septic tank sludge and coffee husks with total N = 4.01%, total P = 0.41%, total K2O = 3.68% and accepting for the Vietnam standards of fertilizer regulations, resulted also illustrated that E.coli concentration in septic tank sludge sample decreased 2.5 - 3.3 times compared to the previous sample. The second one, the composting efficiency was surveyed on the growth of green mustard plant during 31 days by basal fertilizing and top dressing of this compost at 10 days. The growth of the green mustard plant showed the high compost efficiency septic tank sludge and coffee husk based on 28.21cm of height and 62.5g / plant weight. Especially, NT4 combining from septic tank waste, coffee husk with chemical fertilizers was a good formula by getting the best result in all treatment by combined of compost and chemical fertilizer was at the top dressing period, seems the high compost efficiency in helping Brassica juncea grow well by growing green mustard, being 31.25cm of height and 95.83g / plant weight.
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