Summary: Phoma minutispora was repeatedly isolated from skin lesions of two patients. Experimental infection was developed on rabbits and scrapings revealed fungal filaments and ostiolate pycnidia similar to those of P. minutispora. This is the first reported association of P. minutispora with human skin lesions.
Zusammenfassung: Phoma minutispora wurde wiederholt aus Hautläsionen bei zwei Patienten isoliert. Kaninchenhaut ließ sich experimentell infizieren. Der Erreger wurde aus den Krankheitserscheinungen rückisoliert. Dieses ist der erste Bericht über eine Beziehung zwischen Phoma minutispora und Hautveränderungen beim Menschen.
One strain each of granular and downy varieties of Trichophyton mentagrophytesand two strains each of granular and floccose colonial types of Trichophyton rubrum were used for preparation of antigens. The antigens were analyzed by double diffusion against homologous and heterologous antisera raised in rabbits. A total of 17 distinct antigens were recognized, seven of which were common to the two dermatophytes. Granular and downy varieties of these Trichophyton species produced one additional line of nonidentity. Cross reactions failed to establish any relationship between similar morphologic forms of different dermatophytes. One isolate of T. rubrum, which was originally the floccose culture type but changed into the granular form after artificial infection, showed an antigenic relationship to the floccose culture.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.