Background: Congenital malformations are assuming prominence as a contributor to neonatal and childhood mortality. This study is aimed at identifying the pattern and profile of congenital malformations among neonates delivered in a tertiary teaching hospital in Sikkim which will provide baseline data for future studies.Methods: A hospital based cross sectional observational study was conducted from 15 October 2015 till 15 April 2017 among live newborns delivered in the only teaching hospital of Sikkim. Out of 2521 neonates delivered, 96 neonates met the inclusion criteria. These neonates underwent a detailed clinical evaluation and appropriate investigations. Data collected were entered into Microsoft excel worksheet 2017, SPSS (version 22) was used for data analysis.Results: The occurrence of congenital malformations in the hospital was 3.8%. Neonates with major anomalies were 50% and majority of the anomalies were of genitourinary system (23.96%). The relation between gender and congenital malformation was found to be statistically significant with p value <0.05, predominantly affecting male. Only 6.25% of the malformations were diagnosed prenatally.Conclusions: This study gives data on the pattern and profile of malformation from a geographically isolated place in the Himalayan regions of India which showed some significant variation. It also highlights the lack of adequate facilities for prenatal diagnosis of congenital malformation in these regions.
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