EDITORIAL SYNOPSIS This paper correlates the absorption of vitamin B12 with the gastric acidity and with the histological changes in the stomach of patients with simple atrophic gastritis who have no family history of pernicious anaemia. It demonstrates marked impairment of absorption of vitamin B12 in some of them. There is a good but by no means complete correlation between the severity of the gastric atrophy and the depression of gastric function. The bearing of this work on the pathogenesis of Addisonian pernicious anaemia is discussed.
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