A novel silicone hydrogel polymeric material is developed. The preparation method is based on sequential interpenetrating network synthesis. A silicone network is obtained by the interaction between two siloxane oligomers comprising hydride and vinyl functional groups. A hydrophilic network is prepared by radical copolymerization of hydrophilic monomers (N-vinyl pyrrolidone, N,N-dimethylacrylamide) and crosslinking agent (ethylene glycol dimethacrylate). In the hydrated state the developed material has high mechanical properties, transparency, hydrophilicity, oxygen and water permeability. The developed new technology affords obtaining a silicone hydrogel material with a good wettability without additional chemical or plasma surface treatment.
With the aim to synthesize water-dispersible superparamagnetic nanoparticles, iron oxide was precipitated in aqueous solution of dextran, (carboxymethyl)-dextran (CM-dextran), (DEAE-dextran), or D-mannose. Glycidyl methacrylate (GMA) was emulsion-polymerized in the presence of the nanoparticles and the effect of iron oxide modification on the product properties was investigated. The main factors affecting the morphology, size, and size distribution of the latex particles are the type and concentration of emulsifier (Disponil AES 60, Tween 20, Triton X-100) and initiator [ammonium persulfate (APS) and 4,4 0 -azobis(4-cyanovaleric acid) (ACVA)]. Disponil AES 60 and ACVA are the preferred emulsifier and initiator, respectively, because oxirane groups hydrolyzed during the APS-initiated polymerization. Up to some 5 wt % of iron was found in poly(-glycidyl methacrylate) (PGMA) microspheres obtained by emulsion polymerization in the presence of dextran-coated iron oxide and emulsified with Disponil AES 60. The size of magnetic PGMA microspheres could be controlled in the range $ 70-400 nm.
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