Background: Breast cancer is a complex, multifaceted disease encompassing a great variety of entities that show considerable variation in clinical, morphological and molecular attributes. Objective: The aim of this study to evaluate patients' molecular profile (Estrogen receptor, Progesterone receptor, HER2/neu and Ki-67). Patients & Methods: This is a cross-sectional descriptive study was done in Baghdad oncology teaching hospital from December 2015 to April 2016, carried on 100 breast cancer female patients with their age range from 27 to 73 years old and with their histopathology reports and (IHC) results. Results: The highest incidence of breast cancer among patients in 5th (40-49 years) and 6th (50-59 years) decades of life both groups are (32%), estrogen and progesterone values were observed (74% and 75% respectively) and 69 patients (69%) with Ki-67 ≥14. Conclusions: Most of the breast cancer patients in the current study were estrogen and progesterone (Hormonal) positive, and Luminal B-like was the most common molecular subtype (53%) due to high Ki-67 index. There was a strong correlation between estrogen and progesterone in the studied patients with highly significant P value <0.0001.
Comsol multiphysics software is established to make a simulation that is comparable with experimental device. by utilizing comsol, the positive column domain of direct-current glow discharge with argon is considered for both of different applied voltage and working gas pressure. The calculations are exhibited by using a precise collision cross sections and Townsend coefficients for the argon. The impacts of voltage and pressure on the Debye length, number of particles in Debye sphere and plasma frequency are calculated and graphically delineated. With this regard to the dependence of plasma parameters on the applied voltage and pressure, some of them are found to be compatible with the experimental results, while others are not. For example, the calculations of the COMSOL shows that the electron temperature is not always decreasing with the increase in the applied voltage, and the Debye length does not give a linearly decreasing relationship but rather an exponentially decreasing relationship. Also, the calculations do not reproduce and match the experimental results for the dependence electron density on working pressure at various potentials.
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