Purpose: The current COVID-19 pandemic confronts psychiatric patients and mental health services with unique and severe challenges. Methods: In order to identify these trans-national challenges across Europe, an ad-hoc survey was conducted among 23 experts, each answering for one European or aligned country. Results: A number of important themes and issues were raised for the impact of COVID-19 on mental health and mental health services, barriers to service provision and future consequences. A number of key issues were reported by colleagues across several jurisdictions, even though these were at different stages of their national epidemics. Conclusions: Based on these findings, we articulate some important learnings from the early stages of the COVID-19 European pandemic, and highlight key considerations for all countries' mental health services as the current pandemic develops and for future pandemics.
Accumulated evidence has demonstrated abnormal amygdala activation in bipolar disorder (BD). The olfactory bulb (OB) has vigorous connections with the amygdala. Although odor-related functions of the OB decreased during the evolutionary process, we hypothesized that an evolved OB with increased activation in emotion regulation may be one of the main factors affecting amygdala functions in BD. Our aim was to investigate metabolism in the OB and amygdala in patients with BD. Twenty-six patients diagnosed with BD according to DSM-5 diagnostic criteria were included in this cross-sectional study. Metabolism in the OB and amygdala was assessed using fluorodeoxyglucose positron emission tomography/CT in patients with BD. The OB and amygdala metabolism was compared with the patients’
Z
scores. Both OB and amygdala metabolic activities were significantly higher than in the controls. A positive correlation was detected between right/left amygdala metabolism and right OB metabolism (
p
< 0.05, r:467 and r:662, respectively). This study increased our understanding of the etiopathogenesis of BD. In BD, the main cause of hypermetabolism in the amygdala may be increased metabolism in the OB. During evolution, the OB may have assumed a dominant role in emotional processing rather than olfactory functions.
Like children with profound biotinidase deficiency, children with partial biotinidase deficiency are symptom-free at birth. However, the subsequent occurrence of symptoms of profound biotinidase deficiency in our patient with partial deficiency suggests that biotin therapy for this condition may be warranted. It is known that in Turkey marriages between relatives are common. If the neonatal screening program is widened the real ratio can be determined, where marriages between relatives are very high in central Anatolia.
Amaç: Bu çalışmanın amacı madde kullanım bozukluğu (MKB) tanılı hastalarda içselleştirilmiş damgalanma ile tedavi motivasyon ve hastaların klinik özellikleri arasındaki ilişkiyi araştırmaktır
Yöntem: Bu araştırma Haziran 2020-Aralık 2020 tarihleri arasında Gaziantep Üniversitesi psikiyatri servisinde madde kullanım bozukluğu tanısıyla takip ve tedavisi yapılan 63 katılımcıyı içermektedir. Araştırmanın verileri; sosyo-demografik veri ölçeği, içselleştirilmiş damgalanma ölçeği (RHİDÖ) ve tedavi motivasyonu anketi (TİM) kullanılarak toplanmıştır.
Bulgular: Korelasyon analizinde; RHİDÖ toplam ile TİM toplam arasında istatiksel olarak anlamlı bir ilişki saptanmadı. Hastaların madde başlama yaşı ile RHİDÖ algılanan ayrımcılık alt ölçeği arasında istatistiksel olarak anlamlı ve pozitif yönde bir ilişki bulundu. Self mutilasyonu olan hastaların RHİDÖ kalıp yargılar alt ölçeği self mutilasyonu olmayanlardan anlamlı oranda daha yüksekti. İntihar girişimi öyküsü olan hastaların RHİDÖ damgalanmaya direnç alt ölçeği puanı intihar girişimi olmayanlardan daha yüksekti. Hastaların yaşı, madde başlama yaşı, yatış sayısı, eğitim düzeyi, adli öyküsü, self mutilasyon, intihar öyküsü ve ailede madde kullanımı varlığı ile TİM ölçekleri arasında istatistiksel anlamlı ilişki bulunmadı.
Sonuç: Madde kullanım bozukluğu olan hastalarda, içselleştirilmiş damgalanmanın tedavi motivasyonu ile ilişkili olmadığı saptandı. RHİDÖ tüm alt ölçekleri ile birlikte incelendiğinde, madde başlama yaşının, self mutilasyonun ve geçmişte intihar girişimi bulunmasının içselleştirilmiş damgalamayı etkileyebileceği düşünüldü.
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