Adult intraocular neoplasms are most commonly metastases from distal primary malignancies. The same holds true for uveal malignancies. In many uveal malignancies, the intraocular lesion is a harbinger for an, as yet, undiscovered underlying systemic malignancy.
Abstract. Ocular Baylisascaris procyonis infection results from ingestion of infective eggs of B. procyonis, the raccoon ascarid. Herpes simplex virus type 2 (HSV-2) infection of the retina is the result of either primary infection or reactivated disease. Herein, we report a case of a 12-year-old female resident of the Bronx in New York City, who presented with pan-uveitis and vision loss. Initial evaluation for etiologic causes was nondiagnostic. Serology for anti-Baylisascaris procyonis antibodies in serum and vitreous fluid were both positive. Polymerase chain reaction (PCR) of vitreous fluid was positive for HSV-2. Treatment with vitrectomy, albendazole, and acyclovir resulted in mild improvement of visual acuity. The atypical presentation of B. procyonis in this case, as ocular larva migrans with a peripheral granuloma and retinal detachment, underscores the importance of maintaining a high degree of suspicion for this pathogen even in non-diffuse unilateral subacute neuroretinitis (DUSN) patients in urban areas. This case further illustrates that it is possible to have coexisting infections in cases of posterior uveitis.Baylisascaris procyonis is a large ascarid that commonly parasitizes raccoons in North America and Europe.1 It is a common cause of clinical larva migrans in animals and also affects humans, causing either neural larva migrans (NLM) affecting the nervous system and/or ocular larva migrans (OLM) and diffuse unilateral subacute neuroretinitis (DUSN) causing visual impairment.1-3 Animals and humans become infected by ingesting infective eggs from areas or articles contaminated with raccoon feces. 1 We diagnosed a young girl with Baylisascaris OLM, from the Borough of the Bronx in New York City. This patient is of particular interest because she had an atypical presentation for Baylisascaris OLM and was positive for anti-B. procyonis antibodies in her vitreous fluid as well as being seropositive in serum. In addition, polymerase chain reaction (PCR) testing of the vitreous fluid was positive for Herpes simplex virus-2 (HSV-2) DNA. The patient had mild improvement in visual acuity after diagnostic and therapeutic vitrectomy and treatment with albendazole and acyclovir. CASE REPORTThe patient was a 12-year-old female born and raised in the Bronx, New York City, in an area bordering the suburban County of Westchester. She presented to the emergency department of the Jacobi Medical Center, Bronx, New York City, complaining of "redness and pain" in and about her right eye after reportedly being "poked" in that eye 5 days before. Her medical history included perinatal exposure to human immunodeficiency virus (HIV), bronchiolitis, attention deficit hyperactivity disorder, and she wore corrective glasses for astigmatism from age 2 to 7 years. There was a puppy in the household and she reported having played with several stray cats and had seen raccoons in the neighborhood. There was no history of pica and the remainder of the review of systems was negative.Initially, her best corrected visual acuity wa...
BACKGROUND AND OBJECTIVE: To evaluate the impact of anxiety and sleep patterns on intravitreal injection pain. PATIENTS AND METHODS: This prospective, noninterventional study surveyed patients scheduled for intravitreal injection by two retinal surgeons. A standard intravitreal injection technique was used. Patients filled out pre-procedure General Anxiety Disorder-7 (GAD-7) and Pittsburgh Sleep Quality Index (PSQI) questionnaires. Post-procedural pain was assessed with a visual analogue scale. Quality and hours of sleep and anxiety levels were correlated with perceived intravitreal injection pain. RESULTS: A total of 140 patients met inclusion criteria. Mean ± standard deviation scores were 4.9 ± 5.6 for the GAD-7, 6.3 ± 4.1 for the PSQI, and 3.69 ± 2.64 for intravitreal injection pain. Anxiety correlated with intravitreal injection pain (rho = 0.25; P = .003). Previous night's sleep (rho = −0.16; P = .057) and poor sleep quality (rho = 0.14; P = .11) were weakly correlated. Regression analysis revealed anxiety was the only significant predictor of intravitreal injection pain. A 1-point increase in anxiety predicted a 0.10-point increase in intravitreal injection pain (B = 0.10, P = .032). CONCLUSIONS: Anxiety level was the best predictor of perceived pain. This has implications for pre-procedural anxiety screening. [ Ophthalmic Surgery Lasers Imaging Retina . 2021;52:498–504.]
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
hi@scite.ai
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.