Many pregnancies associated diseases are adding to the development of Pregnancy Related Acute
Kidney Injury (PR-AKI) like Pre-Eclampsia/Eclampsia (PE/E), HELLP Syndrome, Antepartum/Postpartum
Hemorrhage (APH/PPH) and Pregnancy Associated Thrombotic Microangiopathy (P-TMA) are common. Puerperal sepsis, septic
abortion, Pre-Eclampsia/Eclampsia, HELLP Syndrome, Antepartum and Postpartum Hemorrhage are common risk factors for
PR-AKI development. PR-AKI patients have adverse impact on the maternal health and may leads to development of CKD even
death.
Background: Chronic kidney disease(CKD) is one of the leading cause of death in the world because of
its late or end stage presentation. In our study we assessed patients of CKD for cognitive dysfunction with
EEG (electroencephalography) and other biochemical parameters. This cross-sectionalstudy was conducted on 60Methods:
newly diagnosed CKDpatients at MGM Medical College and MY Hospital Indore, MP, India, from 2019 to 2021. Baseline
parameters like serum urea, creatinine, bilirubin and sodium were done and patients were subjected to
electroencephalography to assess subclinical uremic encephalopathy and data were analysed using SPSS statistics version
22.0 and p value <0.05 and condence interval more than 95% were considered signicant. In this study, beta wavesResults:
were found to be maximum in stage1 (83.3%) whereas delta waves were found to be more in stage 5 (68%). In CKD stage 1,
16.7% patients had alpha waves and delta waves were absent. In CKD stage 5, 12% & 20% patients were having beta and
alpha waves respectively. Epileptiform discharges were absent in patients of CKD stage 1 with stage 5 CKD having 80%
patients with epileptiform discharges (P value =0.001). All patients in CKD stage1 have symmetrical EEG waves, with 80%
asymmetrical waves were present in CKD stage 5 (P value=0.021). This study supports the fact that as CKDConclusions:
stages progresses, there is propensity of delta waves, asymmetrical waves and epileptiform discharges which helps in early
detection of subclinical uremic encephalopathy and therefore the risk of uremic seizures.
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